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NIX 5% Dermal Cream (Permethrin)

Prescription requiredOnly Available By Prescription
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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Nix 5% Dermal Cream (permethrin) treats lice and scabies. Permethrin, a 1% lotion, effectively treats head lice infections as it targets and eliminates both the lice and their eggs. On the other hand, the 5% cream is explicitly used to treat scabies infections by eradicating the mites responsible for causing scabies.

Before you plan to buy NIX dermal cream to treat lice and scabies, it is crucial to consider factors such as effectiveness, potential side effects, and the NIX dermal cream price.

What is Scabies?

Scabies is an infectious skin condition that results from the infestation of small mites known as Sarcoptes scabiei. These mites burrow into the skin, lay eggs, and trigger itching and a rash. Scabies spread through close contact or sharing infested items. Common symptoms include intense itching, a rash with red bumps or blisters, and potential secondary infections from scratching.

Fact Table
Formula C21H20Cl2O3
License US DailyMed
Bioavailability 60%
Legal status Rx-Only
Chemical Name Permethrin
Elimination half-life 39.5 days
Dosage (Strength) 5%
Pregnancy Appears to be safe
Brands Nix
Protein binding -
PubChem CID 40326
MedlinePlus -
ChEBI 34911
ATC code P03AC04
DrugBank DB04930
KEGG C14388
Routes of administration Topical

Buy NIX 5% Dermal Cream (Permethrin) online from online Canadian Pharmacy |


  • This medication is meant for topical use only.
  • Apply it promptly as prescribed. Stick to the prescribed amount and duration.
  • Always follow the instructions to apply the Cream from head to toe, including nails and skin folds, like between toes.
  • Gently massage the Cream into the skin.
  • After 8-14 hours, you should wash off the Cream by bathing.
  • It is important to prevent contact with the eyes, nose, mouth, or vagina.
  • Even after this Cream eliminates scabies, itching may continue for up to 4 weeks. Ask your doctor about additional medications to relieve itching.


The active ingredient in NIX 5% Dermal Cream is Permethrin.


Inform your doctor if you have any allergies to permethrin or other substances.

Before using NIX dermal cream for scabies, disclose your medical history to your doctor, especially if you have had skin infections or asthma.

Excessive scratching of the skin or scalp can result in a bacterial skin infection. If you notice increased redness or the presence of pus, inform your doctor immediately.

Before using this medication, it is essential to inform your doctor if you are pregnant.


There may be an interaction between this medication and corticosteroids like hydrocortisone and betamethasone. Talk to your doctor about all your medications before you begin your treatment with Nix 5% Dermal Cream.

Side Effects

Nix 5% Dermal Cream can cause side effects like skin irritation, such as redness, itching, or burning at the application site, tingling, or numbness. Rarely, allergic reactions may occur, leading to a rash, swelling, or difficulty breathing.

Frequently Asked Questions about NIX Dermal Cream

Is NIX Dermal Cream over the counter?

NIX Dermal Cream, with 5% permethrin, is a prescription medication for treating scabies. Nix Creme Rinse, containing 1% permethrin, is an over-the-counter product used to treat head lice.

Where can I buy NIX Dermal Cream?

You can buy NIX Dermal Cream at various pharmacies and drugstores. You can buy NIX dermal cream from Canada and Canpharm to get the best price online.

How long does it take for Nix cream to work?

NIX Cream works by paralyzing and killing the mites responsible for causing scabies, as well as eliminating their eggs. While this medication effectively treats scabies infestations, it's important to note that skin itching may take around 2 to 4 weeks to fully resolve after treatment.

Can I leave NIX on overnight?

The recommended duration for leaving NIX on the skin varies depending on the specific product and the treated condition. Nix cream is typically left on for around 10 minutes for head lice before being rinsed off. However, it is generally advised to leave Nix cream on overnight or for 8-14 hours for scabies treatment.

Can lice live after NIX treatment?

While Nix cream is designed to kill lice and their eggs, there is a possibility that some lice or eggs may survive or be missed during treatment. After using the medicine, it may take some time to kill all the lice after using the medicine. To ensure their removal, comb the hair with a fine-toothed nit comb to remove dead and any remaining live lice.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.