Noromby (Enoxaparin)
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Description
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Fact Table
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| Formula | Not applicable (biological molecule) |
| License | FDA approved |
| Bioavailability | ~92% (subcutaneous) |
| Legal status | Prescription Drugs |
| Chemical Name | Enoxaparin sodium |
| Elimination half-life | 4.5 hours (single dose), 7 hours (repeated doses) |
| Dosage (Strength) | 30-150 mg/0.3-1.5 mL (pre-filled syringes) |
| Pregnancy | B (no evidence of risk in humans) |
| Brands | Noromby |
| Protein binding | Low (<10%) |
| PubChem CID | 11953886 |
| MedlinePlus | a601210 |
| ChEBI | 63557 |
| ATC code | B01AB05 |
| DrugBank | DB01225 |
| KEGG | D04703 |
| Routes of administration | Subcutaneous |
Noromby, containing the active ingredient Enoxaparin, is an anticoagulant medication widely used in the prevention and treatment of various thromboembolic disorders. Enoxaparin belongs to the class of drugs known as low molecular weight heparins (LMWHs) and works by blocking the formation of blood clots. It is particularly effective in preventing deep vein thrombosis (DVT), which can lead to pulmonary embolism (PE) in patients undergoing orthopedic surgeries such as knee or hip replacement, or in those who are at risk due to prolonged immobilization. Additionally, Noromby is used in the management of unstable angina and myocardial infarction.
Noromby is administered through subcutaneous injection, ensuring rapid absorption and consistent delivery of medication. This medication is favored for its efficacy in managing clotting disorders without the need for frequent monitoring of blood coagulation parameters, which is typically necessary with other anticoagulants. Before you buy Noromby, it is crucial that you talk to your healthcare provider about potential side effects and Enoxaparin cost.
Directions
Always consult a healthcare provider before beginning treatment with Noromby. The medication is typically prescribed based on body weight, medical condition, and current health status. Noromby is administered via subcutaneous injection. Do not administer this medication intramuscularly. Injections are usually given in the fatty areas of the abdomen, alternating sides with each dose. The dosage varies based on the medical condition being addressed. For most adults undergoing hip or knee replacement surgery, the typical dose is 40 mg once a day with the first dose given approximately 12 hours before surgery.
Ingredients
Active Ingredient: Enoxaparin Sodium
Cautions
Inform your doctor if you have any history of heparin-induced thrombocytopenia (HIT) or allergies to heparin or pork products.
Patients with kidney disease, diabetes, high blood pressure, or any active bleeding (e.g., peptic ulcers) should use Noromby cautiously.
Noromby should only be used during pregnancy when clearly needed.
Older adults may be more sensitive to the effects of Noromby, particularly bleeding.
Interactions
Enoxaparin sodium injection may interact with other medications, which can increase the risk of serious side effects. Inform your healthcare provider about all medications you are taking, especially antiplatelet agents (e.g., aspirin, clopidogrel), other anticoagulants (e.g., warfarin), nonsteroidal anti-inflammatory drugs (NSAIDs; e.g., ibuprofen, naproxen), selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs). Avoid the use of any medication without the knowledge and approval of your healthcare provider while on Noromby.
Side Effects
While Noromby is effective in preventing and treating thromboembolic disorders, it may cause side effects, including bleeding, pain, bruising, redness, or irritation at the injection site.
Frequently Asked Questions about Noromby (Enoxaparin)
What is Noromby (Enoxaparin)?
Noromby (Enoxaparin) is an anticoagulant medication used to prevent and treat blood clots. It is often prescribed to prevent deep vein thrombosis (DVT) and pulmonary embolism (PE), particularly after surgeries or in patients with certain medical conditions.
How does Noromby (Enoxaparin) work?
Enoxaparin works by inhibiting the activity of certain clotting factors in the blood, particularly Factor Xa. This helps to prevent the formation of new clots and stops existing clots from growing larger.
How is Noromby (Enoxaparin) administered?
Noromby is usually administered as a subcutaneous injection (under the skin). The dosage and frequency depend on the patient's condition and response to the medication.
What are the common side effects of Noromby (Enoxaparin)?
Common side effects include bleeding, bruising at the injection site, and mild irritation. Serious side effects, which are less common, can include severe bleeding, allergic reactions, and low platelet counts.
Can I use Noromby (Enoxaparin) if I am pregnant?
Noromby can be used during pregnancy if prescribed by a healthcare provider. It is often preferred over other anticoagulants as it does not cross the placenta. However, it should be used under close medical supervision.
Are there any medications that interact with Noromby (Enoxaparin)?
Yes, several medications can interact with Noromby, including other anticoagulants, antiplatelet drugs, and certain nonsteroidal anti-inflammatory drugs (NSAIDs). It's important to inform your healthcare provider of all medications and supplements you are taking.
What should I do if I miss a dose of Noromby (Enoxaparin)?
If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose to catch up.
How should Noromby (Enoxaparin) be stored?
Store Noromby at room temperature, away from moisture and heat. Keep it out of reach of children and pets. Do not freeze the medication.
Can I consume alcohol while taking Noromby (Enoxaparin)?
It is advisable to limit or avoid alcohol consumption while taking Noromby, as alcohol can increase the risk of bleeding. Consult your healthcare provider for specific recommendations based on your health condition.
What should I do if I experience severe side effects or an overdose of Noromby (Enoxaparin)?
If you experience severe side effects, such as unusual bleeding, dizziness, or difficulty breathing, seek immediate medical attention. In case of a suspected overdose, contact emergency services or go to the nearest emergency room.
