Wait, we have a special
offer for you!

Click the button below to get your discount.

Get my coupon now No thanks, I'd like to pay full price

Use coupon code at checkout:


Use my coupon

Onzetra Xsail (Sumatriptan nasal powder)

Prescription requiredOnly Available By Prescription
Free Shipping on orders over $100

Top brand choice

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


  You'll have option to make 4 interest-free payments by credit card once your order is confirmed using  


Onzestra Xsail is a migraine headache treatment medication available by prescription and taken as a nasal inhalation. It is used to reduce the frequency and severity of migraine headaches and migraines with aura. It is part of the triptan class of drugs and it works by regulating one of the brain's 4 primary neurotransmitters so that blood vessels aren't narrowed the same way. The active ingredient in the medication is Sumatriptan and it also provides pain relief by making certain nerves in the brain less sensitive. Buy Onzestra Xsail 11mg from Canpharm and get the best price on it.

What Is Migraine?

Migraine is a neurological disorder characterized by recurrent headaches that are often intense and accompanied by other symptoms. These headaches are usually throbbing in nature and typically affect one side of the head. Migraines can last for hours to days and can be disabling, causing significant pain and discomfort. In addition to the headache, common symptoms may include nausea, vomiting, sensitivity to light and sound, and visual disturbances. Migraines can be triggered by various factors, such as stress, certain foods, hormonal changes, and environmental stimuli. While the exact cause of migraines is not fully understood, genetics and abnormal brain activity are believed to play a role.

Fact Table
Formula C14H21N3O2S
License US FDA
Bioavailability 15% - 96%
Legal status Rx-Only
Chemical Name Sumatriptan
Elimination half-life 2.5 hours
Dosage (Strength) 11mg 16 Nosepieces
Pregnancy Consult your healthcare provider
Brands Onzetra Xsail
Protein binding 14–21%
PubChem CID 5358
MedlinePlus a614029
ChEBI 10650
ATC code N02CC01
DrugBank DB00669
KEGG D00451
Routes of administration Nasal

Buy Onzetra Xsail (Sumatriptan nasal powder) online from online Canadian Pharmacy |


Use once per day at the first sign of a migraine headache onset

If the headache comes back after the first full dose or you only experience partial relief, you can take a second full dose 2 hours after the first dose. Never take a second dose of this medication any earlier than 2 hours after the first dose, and if you do not experience migraine headache relief, you can see a doctor again.


Pierce the Onzestra capsule when you are ready to take the medication.

Press the white button firmly to pierce the capsule and then release the button.

Piercing is only done once per nosepiece.


Insert the nosepiece into the nostrils and blow into the mouthpiece to deliver a dose.

Use a full dose (2 nosepieces) to treat your headache.


The active ingredient in Onzestra Xsail nasal powder is Sumatriptan.


Let your doctor know of any history of high blood pressure, high cholesterol, diabetes, heart problems, liver or kidney disease, epilepsy, or seizures, or if you smoke before starting on Onzestra Xsail 11mg

Patients with cardiac health problems and at risk of a heart attack may not be suitable for using Onzestra Xsail

Patients using SSRI, SNRI, TCA, and MAOI antidepressant medications may not be suitable for using Onzestra Xsail

Do not take more than a total of 44 mg (two full doses) of Onzestra Xsail in a 24-hour period

Medication may cause dizziness or weakness

Keep the medication out of reach of children and be aware of the medication expiry date


Negative drug interactions may occur between Onzestra Xsail and other Rx medications, including Adderall, Aimovig (erenumab), amitriptyline, chlorzoxazone, duloxetine, Emgality (galcanezumab), gabapentin, hydroxyzine, ketorolac, lamotrigine, meloxicam, methocarbamol, montelukast, ondansetron, oxycodone, Phenergan (promethazine), prednisone, propranolol, tizanidine, Topamax (topiramate), tramadol, trazodone.

Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Onzestra Xsail online.

Side Effects

Side effects from using Onzestra Xsail may occur, and some users may experience runny nose, irritation or tingling in the nose or throat, tiredness, weakness, or flushing. If side effects are experienced, you may want to stop use and meet with a doctor again to discuss migraine headache treatment medication options.

Remember, these are not exhaustive lists, and it's important to consult with a healthcare professional for personalized advice and guidance. If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit or call 1-800-FDA-1088. For complete details about Onzetra Xsail, please refer to Patient Information.

Frequently asked questions about Onzetra Xsail

How to use Onzetra Xsail?

Onzetra Xsail is a medication used to treat migraines. It comes in the form of a nasal powder. To use Onzetra Xsail, follow these steps:

  • Hold the Onzetra Xsail device with your thumb on the gray button and your index and middle fingers on the ridges.
  • Gently insert the nozzle of the device into one nostril until your fingers on the ridges touch your nose.
  • Close the other nostril with your other hand.
  • Breathe in slowly and steadily through your nose, while pressing the gray button on the device to release the medication.
  • Remove the device from your nostril and breathe normally through your mouth.
  • If you still have migraine symptoms, you can repeat these steps for the other nostril, using a new Onzetra Xsail device.

Remember, it's important to read the instructions provided with the medication after consulting with your doctor or pharmacist for guidance on how to use Onzetra Xsail correctly.

How does sumatriptan make you feel?

Sumatriptan is a medication commonly used for the treatment of migraines. It belongs to a class of drugs called triptans. When you take sumatriptan, it narrows the blood vessels in the brain and reducing inflammation, which helps relieve the symptoms of a migraine attack. Sumatriptan can help alleviate migraine symptoms such as headache, sensitivity to light and sound, and nausea. Some individuals may experience relief from their migraine symptoms after taking sumatriptan, while others may not find it as effective. It is always best to consult with your doctor or pharmacist to determine the most suitable treatment option for your specific situation.

What is Onzetra Xsail used to treat?

Onzetra Xsail is a medication that is used for the treatment of migraines. It is designed to provide relief from the symptoms of a migraine attack, such as headache, nausea, and sensitivity to light and sound. Onzetra Xsail delivers medication through the nasal passages using a specialized device, helping to target the migraine directly. However, it neither prevents migraines nor treats other types of headaches.

Is sumatriptan used for anything other than migraines?

Yes, sumatriptan is occasionally used for other conditions besides migraines, but it is primarily prescribed for migraine treatment. In some cases, it may be used off-label for the treatment of cluster headaches, which are severe headaches that occur in cyclical patterns. However, the use of sumatriptan for conditions other than migraines should always be determined by your doctor, as they can assess the potential benefits and risks associated with such use, and whether your conditions warrant its use.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.