Prednefrin Forte Eye drops (Prednisolone Acetate / Phenylephrine Hydrochloride)
Pred Forte
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Description
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Fact Table
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| Formula | Prednisolone Acetate: C23H30O6 Phenylephrine Hydrochloride: C9H13NO2·HCl |
| License | FDA approved (combination may vary by region) |
| Bioavailability | Minimal systemic absorption when used ophthalmically |
| Legal status | Prescription Drug |
| Chemical Name | Prednisolone Acetate: 11ß,17a,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate Phenylephrine Hydrochloride: (R)-1-(3-hydroxyphenyl)-2-methylaminoethanol hydrochloride |
| Elimination half-life | Prednisolone: ~2–3 hours Phenylephrine: ~2–3 hours |
| Dosage (Strength) | Prednisolone Acetate 1% w/v + Phenylephrine Hydrochloride 0.12% w/v |
| Pregnancy | Consult Doctor (Category C) |
| Brands | Prednefrin Forte |
| Protein binding | Prednisolone: ~90–95% Phenylephrine: Not well defined |
| PubChem CID | Prednisolone Acetate: 59949 Phenylephrine Hydrochloride: 6041 |
| MedlinePlus | Prednisolone: a682793 |
| ChEBI | Prednisolone Acetate: 8376 Phenylephrine Hydrochloride: 8093 |
| ATC code | S01CB20 (combination product) |
| DrugBank | Prednisolone Acetate: DB00860 Phenylephrine Hydrochloride: DB00388 |
| KEGG | Prednisolone Acetate: D00472 Phenylephrine Hydrochloride: D08320 |
| Routes of administration | Ophthalmic (eye drops) |
Prednefrin Forte is a post-surgery anti-inflammatory medication used after eye surgery that may also be prescribed for severe eye inflammation caused by allergies, injury, or exposures. Prednisolone acetate and phenylephrine hydrochloride are corticosteroid drugs that suppress the inflammatory response so that there is less pain, swelling, and redness in the eye and the person is in much less discomfort after surgery or because of eye allergies. You can buy Prednefrin eye drops with a prescription here at Canpharm.
Directions
Standard directions for dosage are to apply eye drops to affected eyes 2 – 4x a day as indicated in your prescription
Ingredients
The active ingredients in Prednefrin Forte are prednisolone acetate and phenylephrine hydrochloride
Cautions
Let your doctor know of any history of cataracts, glaucoma, myopia (severe nearsightedness), diabetes, or eye surgery before starting on Prednefrin Forte
Following administration of these drops you may experience temporary blurring of vision and it may be advisable to avoid driving or operating machinery until vision clears
Women who are pregnant or breastfeeding should only take this medication if their doctor approves it
Be aware of medication expiry date
Interactions
Negative drug interactions may occur between Prednefrin Forte and other Rx medications, including albuterol, amlodipine, atorvastatin, doxycycline, furosemide, gabapentin, hydrochlorothiazide, ibuprofen, levothyroxine, atorvastatin, lisinopril, losartan, metformin, esomeprazole, omeprazole, prednisone, simvastatin, levothyroxine, tramadol, and cetirizine. Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Prednefrin eye drops.
Side Effects
Prednefrin Forte side effects may occur and some users may experience temporary stinging or burning sensation in the eye after application. If side effects are seen you may want to discontinue use and meet with a doctor again to discuss eye inflammation treatment medication alternatives
Frequently Asked Questions about Prednefrin Forte Eye Drops
What are Prednefrin Forte Eye Drops used for?
Prednefrin Forte Eye Drops are used to treat eye inflammation and redness caused by conditions like uveitis, allergic conjunctivitis, or following eye surgery.
How do Prednefrin Forte Eye Drops work?
The prednisolone acetate in the drops reduces inflammation, while the phenylephrine hydrochloride helps constrict blood vessels to reduce redness in the eyes.
How should Prednefrin Forte Eye Drops be used?
Apply the prescribed number of drops into the affected eye(s), typically 1–2 drops 2–4 times a day or as directed by your doctor.
What are the side effects of Prednefrin Forte Eye Drops?
Possible side effects include eye irritation, blurred vision, eye discomfort, increased intraocular pressure, or sensitivity to light.
How long does it take for Prednefrin Forte Eye Drops to work?
Prednefrin Forte typically begins to reduce inflammation and redness within a few hours, but full effects may take 1–2 days.
Can Prednefrin Forte be used long-term?
Long-term use should be avoided unless advised by a doctor, as prolonged use of steroids can lead to eye pressure increase, cataracts, or other complications.
Who should not use Prednefrin Forte Eye Drops?
It should not be used by individuals with viral eye infections, fungal infections, or glaucoma unless directed by a healthcare provider.
Can I wear contact lenses while using Prednefrin Forte?
It is advised to avoid wearing contact lenses while using Prednefrin Forte unless otherwise recommended by your doctor.
Can Prednefrin Forte Eye Drops cause increased eye pressure?
Yes, prolonged use of steroid eye drops like Prednefrin Forte can increase intraocular pressure, potentially leading to glaucoma.
What should I avoid while using Prednefrin Forte Eye Drops?
Avoid touching the tip of the dropper to any surface, including your eye, to prevent contamination, and avoid using other eye medications unless advised by your doctor.
