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Preparation H Hemorrhoidal Suppositories Biodyne

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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Preparation H suppositories are an OTC hemorrhoid treatment medication available without a prescription and used to relieve the burning, itching, and discomfort that occur when a person has developed a hemorrhoid. Preparation H for hemorrhoids is formulated to shrink hemorrhoidal tissue and they work well when inserted overnight for less severe piles the next morning. Buy Preparation H suppositories from Canada and Canpharm and get the best price on them.

What are Hemorrhoids?

Hemorrhoids is a condition where veins in or around the rectum and anus become swollen and inflamed. The person will experience irritation, discomfort, and in some cases pain in the affected area and hemorrhoids can be caused by straining during bowel movements, prolonged periods seated, obesity, straining from lifting, or eating a diet that doesn't have enough fiber. Women may also get hemorrhoids when pregnant. As people age there is more of a chance of getting hemorrhoids.

Fact Table
Formula C9H13NO2
License US FDA, US DailyMed
Bioavailability 38%
Legal status Rx-Only
Chemical Name Phenylephrine HCL
Elimination half-life 2.1–3.4 h
Dosage (Strength) 48 (Count)
Pregnancy Consult Doctor
Brands Preparation H
Protein binding 95%
PubChem CID 6041
MedlinePlus a606008
ChEBI 8093
ATC code C01CA06
DrugBank DB00388
KEGG D08365
Routes of administration Rectal

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Ensure the bowel is empty and area is clean and use for thumb and forefinger to insert suppository into rectum until it passes the muscle sphincter. Hold buttocks for 5 seconds and for some people it is helpful to remain lying down for 5 minutes. Repeat up to 6 times daily as needed for hemorrhoid relief.


The active ingredient in Preparation H is Phenylephrine HCI.


Only insert one suppository for each treatment instance. If suppository is not effective for hemorrhoid relief, you can speak to your pharmacist about other treatment approaches.

See doctor if you experience bleeding from hemorrhoids before or after using this medication

Do not remove suppository from wrapping until just before insertion

Do not use medication past its expiry date


There are no established drug interactions risks between Preparation H for hemorrhoids suppositories and other OTC or Rx medications. If you have any concerns about interactions, you can bring them up with the pharmacist before you buy Preparation H suppositories online.

Side Effects

Preparation H suppository side effects may occur, and some users may experience irritation at the application site. If side effects are experienced it may be best to stop use and meet with a pharmacist again to discuss hemorrhoid treatment medication alternatives.

Remember, these are not exhaustive lists, and it's important to consult with a healthcare professional for personalized advice and guidance. If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit or call 1-800-FDA-1088

Frequently Asked Questions about Preparation H Suppositories

Do Preparation H Suppositories Make You Poop?

No, these suppositories do not have any laxative effect and will not promote a bowel movement.

How often can I use Preparation H suppositories?

You can use Prep H suppositories up to 6 times each day.

Can you use cream and Preparation H suppositories together?

Yes, you can use a suppository and a hemorrhoid cream at the same time.

Are Preparation H suppositories safe during pregnancy?

Yes, it is safe to use these suppositories while you are pregnant.

Can I use expired Preparation H suppositories?

You can use expired suppositories, but they may be significantly less effective for treating hemorrhoids compared to Prep H suppositories that have not passed their expiry date.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.