Rapamune (Sirolimus)

This medicine is an immunosuppressant used to prevent organ rejection after a kidney transplant. It may also be used to treat other conditions as determined by your doctor.

Directions

Follow the directions for using this medicine provided by your doctor. Ask your doctor, nurse, or pharmacist any questions you may have about this medicine. THIS MEDICINE MAY BE TAKEN on an empty stomach or with food. Always take it the same way, either with food or on an empty stomach. TAKE THIS MEDICINE at the same time each day. IF YOU ARE ALSO TAKING CYCLOSPORINE, take this medicine 4 hours after your cyclosporine dose unless otherwise directed by your doctor. DO NOT EAT GRAPEFRUIT OR DRINK GRAPEFRUIT JUICE AT ANY TIME WHILE TAKING THIS MEDICINE. STORE THIS MEDICINE at room temperature between 68 and 77 degrees F (20 and 25 degrees C) in a tightly-closed and light-resistant container, away from heat and light. Protect from direct sunlight. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do NOT take 2 doses at once.

Cautions

Warning:

Rapamune decreases the action of the immune system. This may increase your risk for infection. It may also increase your risk for developing certain types of cancer (eg, lymphoma). Tell your doctor right away if you notice signs of infection (eg, persistent sore throat, chills, fever) or unusual growths or lumps. Rapamune may increase the risk of severe side effects, including death, when used with certain other immunosuppressants in liver or lung transplant patients. Use of Rapamune in liver or lung transplant patients is not recommended.