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Revolution (Monthly) (Selamectin)

Also Known as Stronghold

Prescription requiredOnly Available By Prescription
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What is Generic?

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Revolution is a dog and cat flea and tick treatment medication available by prescription, but it is also a multi-spectrum parasiticide that can control parasitic worms and mites too. It only needs to be applied topically on the pet once a month, and the active ingredient in Revolution (Selamectin) works by creating an electrolyte balance in the nerves and muscle cell of parasites, causing paralysis and eventually death. It is best to apply this solution once a month at the same time each month. Buy Revolution for dogs from Canada and Canpharm and get the best price on it.

Fact Table
Formula C43H63NO11
License FDA approved
Bioavailability Not readily available; designed for topical use
Legal status Prescription only
Chemical Name Selamectin
Elimination half-life Approximately 10 days in cats; varies in dogs
Dosage (Strength) Available in doses for animals of different weights (e.g., 15 mg for cats and dogs under 22 lbs)
Pregnancy advice Use only if necessary and according to the veterinarian's advice
Brands Revolution, Zoetis
Protein binding High (approximately 98%)
PubChem CID 9577382
MedlinePlus Not applicable to veterinary medicine
ChEBI Not listed
ATC code QP54AB05
DrugBank DB11427
KEGG Not listed
Routes of administration Topical

Buy Revolution (Monthly) (Selamectin) online from online Canadian Pharmacy |


Dosage strengths and guidelines are based on weight and may vary based on the specific treatment / prevention aim as discussed with your veterinarian. You should always administer this medication exactly as shown in your prescription.

Part fur of animal at base of neck immediately between the shoulder blades

Apply full contents of one product applicator to dry skin and allow it to be absorbed into skin natural. Do not touch or attempt to rub into skin.

If you wish to bathe your pet after applying Revolution for cats or Revolution for dogs you should wait at least 2 hours after the application

Keep medication away from mouth, nose, and ears and do not allow your pet to ingest Revolution


The active ingredient in Revolution is Selamectin


For use with dogs aged 6 weeks and up, and cats aged eight weeks and up

Let your veterinarian know of your pet having any history of previous heartworm infections or any condition that can weaken their immune system before having them start on Revolution

Medication is flammable and should be kept away from heat, sparks, open flames or any other source of ignition

Dogs with existing heartworm infections may not be suitable for using Revolution as the medication is not effective for adult D. immitis and Revolution is not effective for microfilariae clearance.

Keep pet medication in a cool, dry place below 30 degrees Celsius (86F) and out of the reach of children


There are no established drug interactions risks between Revolution for cats and other pet Rx or OTC medications, but it is always a good idea to let your doctor know of all medications your pet is currently taking before getting a prescription and proceeding to buy Revolution for dogs online.

Side Effects

Revolution side effects may occur, and some users may experience irritation or hair loss at application stie, vomiting, diarrhea, appetite loss, lethargy, drooling, labored breathing, tremors, conjunctivitis, sneezing, or fever. If side effects are experienced it may be best to stop use and meet with your veterinarian again to discuss flea and tick killer medication alternatives.

Remember, these are not exhaustive lists, and it's important to consult with a healthcare professional for personalized advice and guidance. If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit or call 1-800-FDA-1088

Frequently Asked Questions about Revolution for Cats

Is Revolution really safe for cats?

Revolution flea medication is safe for all pets, including cats, provided you adhere to dosage regulations and apply the medicated solution in the right location and with every other method instruction shown to you in the prescription.

What if my cats lick off Revolution?

It is made very clear to pet owners that Revolution is to be applied topically at the base of the neck in between the shoulder blades. The reason for this is that a cat is physically unable to reach that part of their body and lick it, so if you apply Revolution properly there is not a chance your cat will be able to lick off the medication.

Can I buy Revolution over the counter?

No, you will need to have a veterinarian’s prescription in order to buy this medication from a pharmacy.

What’s the difference between Revolution and Revolution Plus?

Revolution and Revolution Plus are different in that Revolution Plus is able to eliminate a larger number of parasites, while Revolution is only for fleas, ticks, heartworms, and mites.

Do vets recommend Revolution for dogs?

Yes, veterinarians regard Revolution as a reliable and effective flea, tick, and heartworm prevention medication and will usually recommend it to pet owners quite readily.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.