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Rupall (rupatadine fumarate)

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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Rupatadine belongs to the class of medications called second-generation antihistamines, specifically the class known as histamine receptor antagonists. It works by blocking the action of one of the body's natural chemicals known as histamine. Histamine is responsible for many of the symptoms caused by allergies. Rupatadine is used for the relief of symptoms associated with seasonal and year-round allergies, including sneezing, itchy and runny nose, and tearing and redness of the eyes. It is also used for the relief of symptoms associated with allergic skin conditions, including chronic hives, itching, and other skin disorders. Rupatadine usually starts working within 2 hours and lasts for 24 hours.

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The recommended dose of rupatadine for adults and adolescents 12 years of age and older is 10 mg taken by mouth once daily. The dose for children 2 to 11 years old is based on body weight. Children weighing 10 kg to 25 kg should be given 2.5 mg (2.5 mL) taken by mouth once daily. Children weighing more than 25 kg should take 5 mg (5 mL) by mouth once daily. Use an oral syringe to measure each dose of the liquid, as it gives a more accurate measurement than household teaspoons. Wash the syringe after each use. This medication may be taken with food or on an empty stomach. Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor. It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice. Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children. Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.


The active ingredient in Rupall is Rupatadine.


Abnormal heart rhythms: This medication can cause abnormal heart rhythms. Certain medications (e.g., sotalol, quinidine, thioridazine, chlorpromazine, droperidol, pimozide, gatifloxacin, moxifloxacin, mefloquine, pentamidine, arsenic trioxide, probucol, tacrolimus) can increase the risk of a type of abnormal heart rhythm called QT prolongation, and should not be used in combination with rupatadine. You are more at risk for this type of abnormal heart rhythm and its complications if you: • are female • are older than 65 years of age • have a family history of sudden cardiac death • have a history of heart disease or abnormal heart rhythms • have a slow heart rate • have congenital prolongation of the QT interval • have diabetes • have had a stroke • have low potassium, magnesium, or calcium levels • have nutritional deficiencies If you have heart disease and abnormal heart rhythms, or people are taking certain medications (e.g., verapamil, atazanavir), discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Kidney function: The safety and effectiveness of this medication have not been established for people with reduced kidney function. This medication is not recommended for people with reduced kidney function. Liver function: The safety and effectiveness of this medication have not been established for people with reduced liver function. This medication is not recommended for people with reduced liver function. Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately. Breast-feeding: It is not known if rupatadine passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding. Children: The tablet form of this medication is not recommended for children less than 12 years of age. The safety and effectiveness of using this medication have not been established for children younger than 2 years of age. Seniors: Seniors may be more likely to experience side effects with this medication.

Side Effects

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time. Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects. • diarrhea • dizziness • drowsiness • dry mouth • headache • nausea • red eyes • tiredness • vomiting • weakness Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention. Check with your doctor as soon as possible if any of the following side effects occur: • increased frequency of cold or flu symptoms (e.g., chills, fever, sore throat, cough, nasal congestion, runny nose) • signs of muscle damage (e.g., unexplained muscle pain, tenderness or weakness, or brown or discoloured urine) Stop taking the medication and seek immediate medical attention if any of the following occur: • signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat) • symptoms of abnormal heart rhythm (e.g., fast, slow or pounding heartbeat, cold sweats, feeling faint, lightheadedness, nausea, shortness of breath)