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Rupall (rupatadine fumarate)

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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Rupall falls under the category of second-generation antihistamines, specifically within the group referred to as histamine receptor antagonists. Its mechanism involves inhibiting the activity of histamine, a natural compound in the body. Histamine is responsible for numerous allergy symptoms. Rupatadine is employed to alleviate symptoms linked to both seasonal and perennial allergies, such as sneezing, nasal itchiness, runny nose, and eye irritation. Moreover, it is utilized to alleviate symptoms related to allergic skin conditions like chronic hives, itching, and various dermatological issues. Typically, Rupatadine begins to take effect within two hours of ingestion and remains active for 24 hours.

Before you buy Rupall, it is crucial that you talk to your healthcare provider about its effectiveness and potential side effects.

Fact Table
Formula C23H25ClN2O2 * C4H4O4
License Approved in various countries
Bioavailability Not Available
Legal status Varies by country (Rx/OTC)
Chemical Name Rupatadine fumarate
Elimination half-life 5.9 hours (approx.)
Dosage (Strength) Usually 10mg tablets
Pregnancy Consult a doctor
Brands Rupall, Rupafin, others
Protein binding 98-99%
PubChem CID 53292
MedlinePlus Not Assigned
ChEBI CHEBI:135473
ATC code R06AX28
DrugBank DB11614
KEGG D09069
Routes of administration Oral (tablet)

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For adults and children aged 12 years and older, the recommended dosage of Rupall 10 mg is one tablet taken orally once daily, preferably with water, with or without food. It is important to follow the dosage instructions provided on the packaging or as directed by your healthcare professional. Never exceed the recommended dosage unless advised by a healthcare provider.


Each tablet of Rupall medication contains rupatadine fumarate as the active ingredient.


Before taking Rupall, inform your healthcare provider about any existing medical conditions you may have, especially liver or kidney problems.

Avoid consuming alcohol while taking Rupall, as it may increase the risk of drowsiness and other side effects.

Do not exceed the recommended dosage of Rupall, as it may lead to adverse effects.

If you are pregnant or breastfeeding, consult your doctor before using Rupall to assess the potential risks and benefits.


Rupall may interact with certain medications such as ketoconazole, erythromycin, and other drugs that inhibit the enzyme CYP3A4. Avoid combining Rupall with other antihistamines or sedatives, as it may increase the risk of drowsiness and impair your ability to perform tasks that require alertness. Make sure to disclose all the medications you are presently using to your healthcare provider to prevent any possible interactions.

Side Effects

While Rupall is generally well-tolerated, some individuals may experience side effects. Common side effects include:

  • Drowsiness
  • Headache
  • Fatigue
  • Dry mouth
  • Nausea
  • Dizziness

Frequently Asked Questions about Rupall (rupatadine fumarate)

What is Rupall (rupatadine fumarate)?

Rupall (rupatadine fumarate) is a medication that belongs to the class of second-generation antihistamines, specifically known as histamine receptor antagonists.

What is Rupall used for?

Rupall is indicated for the symptomatic relief of nasal and non-nasal symptoms of seasonal allergic rhinitis (SAR) and perennial allergic rhinitis (PAR) in patients 2 years of age and older. It is also used for the relief of symptoms associated with allergic skin conditions, including chronic hives, itching, and other skin disorders.

How does Rupall work?

Rupall works by blocking the action of one of the body’s natural chemicals known as histamine. Histamine is responsible for many of the symptoms caused by allergies.

How quickly does Rupall work?

Rupall usually starts working within 2 hours and lasts for 24 hours.

What are the forms of Rupall available?

Rupall is available in two forms: a tablet containing 10 mg of rupatadine and an oral solution containing 1 mg/mL of rupatadine.

What are the nonmedicinal ingredients in Rupall?

The nonmedicinal ingredients in Rupall tablets include lactose monohydrate, magnesium stearate, microcrystalline cellulose, pregelatinised maize starch, red iron oxide, and yellow iron oxide. The oral solution contains banana flavor, citric acid anhydrous, disodium phosphate anhydrous, methyl parahydroxybenzoate, propylene glycol, purified water, quinoline yellow, saccharin sodium, and sucrose.

How should I use Rupall?

The recommended dose of rupatadine for adults and adolescents 12 years of age and older is 10 mg taken by mouth once daily. The dose for children 2 to 11 years old is based on body weight.

Can I give Rupall to someone else?

No, you should not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

What should I do if I have not discussed this medication with my doctor?

If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

What are the side effects of Rupall?

For information about the side effects of Rupall, please consult your healthcare provider or pharmacist, as they can provide you with a comprehensive list based on your health condition and history.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.