Sensodyne Repair and Protect Toothpaste with 5% Novamin
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Fact Table
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| Formula | NovaMin: no discrete molecular formula; calcium sodium phosphosilicate bioactive glass composed of CaO–Na2O–P2O5–SiO2; sodium fluoride: NaF |
| License | Marketed as a non-prescription dental toothpaste; Canadian product lists medicinal ingredients calcium sodium phosphosilicate (NovaMin) and sodium fluoride |
| Bioavailability | Not applicable; topical dental product not intended for systemic absorption |
| Legal status | Over-the-counter / non-prescription dental product |
| Chemical Name | Calcium sodium phosphosilicate (NovaMin); sodium fluoride |
| Elimination half-life | Not applicable; topical dental mineral/glass ingredient |
| Dosage (Strength) | Calcium sodium phosphosilicate (NovaMin) 5.0% w/w plus sodium fluoride 0.2299% w/w, equivalent to fluoride 0.104% w/w; brush twice daily and spit out |
| Pregnancy | No specific pregnancy restriction identified for topical toothpaste use as directed; avoid swallowing and consult a dentist or healthcare professional if concerned |
| Brands | Sensodyne Repair and Protect; Sensodyne Repair and Protect Extra Fresh; Sensodyne Repair and Protect Whitening |
| Protein binding | Not applicable |
| PubChem CID | NovaMin/calcium sodium phosphosilicate: not assigned as a discrete compound; sodium fluoride: 5235 |
| MedlinePlus | No dedicated Sensodyne/NovaMin monograph; fluoride: a682727 |
| ChEBI | NovaMin/calcium sodium phosphosilicate: not assigned; sodium fluoride: 28741 |
| ATC code | A01AA51 (sodium fluoride, combinations); A01AA01 (sodium fluoride) |
| DrugBank | NovaMin/calcium sodium phosphosilicate: not assigned; sodium fluoride: DB09325 |
| KEGG | NovaMin/calcium sodium phosphosilicate: not assigned; sodium fluoride: D00943; C08142 |
| Routes of administration | Topical dental use; toothpaste applied to teeth during brushing |
Sensodyne Repair & Protect is a toothpaste used to relieve tooth sensitivity while protecting against cavities. Its active ingredient, stannous fluoride, works by forming a protective layer over sensitive areas of the tooth to help block pain caused by cold, heat, acids, sweets, and contact. It is available in several varieties including Mint, Extra Fresh, and Whitening, and is intended for adults and children 12 and older.
Directions
Apply at least a 1-inch strip of the product onto a soft bristle toothbrush. Brush teeth thoroughly for at least 1 minute twice a day (morning and evening), and not more than 3 times per day, or as recommended by a dentist or doctor. Minimize swallowing and spit out after brushing. Children under 12 years of age should consult a dentist or doctor before use.
Ingredients
The active ingredient in Sensodyne Repair and Protect is stannous fluoride 0.454% (0.15% w/v fluoride ion). Inactive ingredients may include glycerin, PEG-8, hydrated silica, pentasodium triphosphate, flavor, sodium lauryl sulfate, titanium dioxide, polyacrylic acid, silica, cocamidopropyl betaine, and sodium saccharin.
Cautions
Before using this medication, you may want to consult a healthcare provider about the following:
- Any existing health conditions
- Any allergies
- A list of all medications currently being taken
If sensitivity persists after 4 weeks of regular use, or if the problem worsens, stop use and see a dentist, as it may indicate a more serious dental condition that requires prompt care.
Children under 12 years of age should consult a dentist or doctor before using this product.
Keep out of reach of children under 6 years of age. If more than the amount used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away.
Do not store above 30 degrees Celsius, or 86 degrees Fahrenheit.
Contraindications
Avoid taking or using this medication if any of the following apply:
- You have a known allergy or hypersensitivity to stannous fluoride or any of the other ingredients in Sensodyne Repair & Protect
Side Effects
Side effects from Sensodyne Repair & Protect are uncommon when used as directed. Some people may experience:
- Mild irritation of the gums or soft tissues of the mouth
- Temporary staining of the teeth, which can occur with stannous fluoride products
- Mild alteration in taste
If irritation occurs or persists, discontinue use and consult your dentist.
If you experience any allergic reaction, such as rash, itching, or swelling, stop use immediately and seek medical attention.
Frequently Asked Questions about Sensodyne Repair & Protect Toothpaste with 5% NovaMin
What is Sensodyne Repair & Protect Toothpaste with 5% NovaMin?
Sensodyne Repair & Protect with 5% NovaMin is a daily fluoride toothpaste made for people with sensitive teeth. In the Canadian product information, the medicinal ingredients are calcium sodium phosphosilicate, also called NovaMin, 5.0% w/w, and sodium fluoride 0.2299% w/w, providing fluoride 0.104% w/w.
What is it used for?
It is used to help relieve and protect against tooth sensitivity when brushing twice daily. It also provides everyday cavity protection because it contains fluoride.
What is NovaMin?
NovaMin is calcium sodium phosphosilicate, a bioactive glass ingredient designed to help form a mineral-like repairing layer over exposed dentin, the sensitive inner tooth surface. This helps block exposed dentin tubules that can trigger sensitivity pain.
How does Sensodyne Repair & Protect help sensitive teeth?
When used regularly, NovaMin helps build a protective layer over vulnerable sensitive areas of the teeth. This barrier helps reduce sensitivity from triggers such as cold, heat, sweet foods, acidic foods, or brushing.
How should it be used?
Adults and children 12 years and older generally brush thoroughly at least twice daily, then spit out the toothpaste rather than swallowing it. Product directions commonly advise following the label, keeping the cap closed, and not using more often than directed.
How long does it take to work?
Sensitivity relief usually depends on consistent use. Sensodyne describes Repair & Protect as providing lasting sensitivity protection with twice-daily brushing, and continued daily use helps maintain the benefit.
Can it repair cavities or rebuild enamel?
No. The “repair” claim refers to forming a protective mineral layer over sensitive exposed dentin areas, not filling cavities, reversing advanced decay, or replacing dental treatment. Tooth pain, visible decay, broken teeth, or persistent sensitivity should be assessed by a dentist.
Who should not use it?
Sensodyne toothpaste is generally not recommended for children under 12 unless advised by a dentist or doctor. People who develop irritation should stop use, and swelling of the mouth or face should be treated as a reason to seek medical or dental advice promptly.
Are there side effects?
Most people tolerate sensitivity toothpaste well, but possible problems include mouth irritation, gum irritation, unpleasant taste, or allergic-type reactions. Swelling of the mouth or face is not expected and should be addressed promptly.
Is the 5% NovaMin version available everywhere?
No. Sensodyne formulations vary by country and product line. Some Repair & Protect products contain 5% NovaMin, while other market versions may use different active ingredients, so the package label is the best source for confirming the exact formula.
