-
Description
-
Reviews (0)
-
Related Products
-
Related Conditions
Fact Table
| Fact Table | |
|---|---|
| Formula | C26H26F2N2 |
| License | Approved in some countries (not FDA approved) |
| Bioavailability | ~40–50% |
| Legal status | Prescription Drug |
| Chemical Name | 1-[Bis(4-fluorophenyl)methyl]-4-(2-phenylethyl)piperazine |
| Elimination half-life | ~18 days (due to high lipid solubility and tissue binding) |
| Dosage (Strength) | 5 mg, 10 mg tablets |
| Pregnancy | Consult Doctor (Safety not established) |
| Brands | Sibelium, Flunarizine |
| Protein binding | ~90% |
| PubChem CID | 3373 |
| MedlinePlus | Not available |
| ChEBI | 31432 |
| ATC code | N07CA03 |
| DrugBank | DB12443 |
| KEGG | D01286 |
| Routes of administration | By mouth |
Sibelium is a migraine prevention medication that may also be used to treat vertigo or as part of refractory epilepsy treatment. Flunarizine is a calcium-channel blocker drug that dilates coronary and systemic arteries and the reduction in blood pressure means migraine headaches or vertigo are less likely to happen or be less severe. Sibelium may also be prescribed for occlusive peripheral vascular disease treatment, and it may also be taken at a low dosage to stop motion sickness. You can buy Sibelium with a prescription here at Canpharm.
Directions
Standard dosage for this medication is to take one 10mg Sibelium tablet 1x daily. Dosage may be reduced to 5mg tablet 1x daily for adults over 65 years of age. Maintenance dosage for migraine prevention may be a 5-days on / 2-days off for up to 6 months
Take Sibelium at night
Ingredients
The active ingredient in Sibelium is Flunarizine dihydrochloride
Cautions
Let your doctor know of any history of Parkinson's disease, Porphyria, heart disease, liver or kidney disease, extrapyramidal syndrome, depression, sleep disorders, urinary tract obstruction, vision problems, or gastrointestinal blockages before starting on Sibelium medication
Use of this medication will not be suitable for patients with severe hepatic impairment and receiving dialysis treatments
Women who are pregnant or plan to become pregnant should only use this medication if their doctor approves it. This will apply for mothers who are breastfeeding too.
Keep medication out of direct sunlight and be aware of expiry date
Interactions
Negative drug interactions may occur between Sibelium and other Rx or OTC medications, including phenytoin, carbamazepine, phenobarbital, codeine, hydrocodone, zolpidem, lorazepam, alprazolam, cyclobenzaprine, carisoprodol, cetirizine, and phenothiazines medications. Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Sibelium online.
Side Effects
Sibelium side effects may occur, and some users may experience tiredness, weakness, increased appetite, constipation, nauseas, vomiting, drowsiness, headache, or increased sweating. If side effects are seen you may want to discontinue use and meet with a doctor again to discuss migraine headache prevention medication alternatives.
Frequently Asked Questions about Sibelium (Flunarizine)
What is Sibelium used for?
Sibelium (flunarizine) is used to prevent and treat migraine headaches and vertigo (dizziness) associated with balance disorders.
How does Sibelium work?
Sibelium works by blocking calcium channels in the brain and reducing the activity of neurotransmitters, which helps prevent migraines and control vertigo symptoms.
How should Sibelium be taken?
Sibelium is usually taken once daily, with or without food, as directed by your doctor. The dosage may vary depending on the condition being treated.
What are the side effects of Sibelium?
Common side effects include drowsiness, weight gain, dry mouth, and gastrointestinal issues like nausea. Serious side effects may include depression or extrapyramidal symptoms (movement disorders).
How long does it take for Sibelium to work?
Sibelium may take a few weeks to show full benefits in preventing migraines, while it may relieve vertigo symptoms more quickly.
Who should not take Sibelium?
Sibelium should not be taken by individuals with a history of depression, Parkinson's disease, or other movement disorders, and those with hypersensitivity to flunarizine or any of its components.
Can Sibelium interact with other medications?
Yes, Sibelium can interact with other medications, especially sedatives, antidepressants, and other CNS-active drugs. Always inform your doctor of any other medications you are taking.
Can Sibelium cause weight gain?
Yes, weight gain is a known side effect of Sibelium, although not everyone will experience it.
How should Sibelium be stored?
Sibelium should be stored at room temperature, away from moisture and direct light, and kept out of reach of children.
Can I stop taking Sibelium suddenly?
It is recommended to gradually reduce the dosage of Sibelium under the guidance of your doctor rather than stopping it abruptly to avoid withdrawal symptoms.
