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Sitavig (Acyclovir)

Prescription requiredOnly Available By Prescription
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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Sitavig is an antiviral medication used for treatment of cold sores caused by the herpes simplex virus and is available by prescription. The active ingredient in the medication works to eventually eliminate the virus and makes outbreaks shorter and less severe. It also aids in making the sores heal faster along with preventing new cold sores from developing and minimizing any pain or itching. Sitavig may also be prescribed to treat genital herpes. Buy Sitavig from Canada and Canada and get the lowest on the medication.

What is a Herpes Simplex Infection?

The herpes simplex virus is a common infection that is spread by skin-to-skin contact and cause painful blisters or ulcers. Type one is the HSV-1 virus that is spread by oral contact and will cause infections around the mouth, including cold sores. HSV-2 is spready by sexual contact and causes genital herpes. It is not uncommon for people to have no symptoms or only very mild symptoms from an infection, but it is also possible to have recurrent herpes infection with either type.

Fact Table
Formula C8H11N5O3
License FDA approved
Bioavailability 15-30% orally; significantly higher when applied topically
Legal status Prescription only (Rx)
Chemical Name Acyclovir
Elimination half-life 2.5 to 3.3 hours in individuals with normal renal function
Dosage (Strength) Buccal tablets: 50 mg
Pregnancy advice Category B (No evidence of risk in humans)
Brands Sitavig, Zovirax
Protein binding 9 to 33%
PubChem CID 135398742
MedlinePlus a681045
ChEBI 2453
ATC code J05AB01
DrugBank DB00787
KEGG D00222
Routes of administration Oral, topical, intravenous (IV)

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Remove one tablet from the blister pack and place it in mouth. Locate it on the upper gum just above the left or right incisor tooth. Push firmly into place, and after placement remove hand from mouth and gently press your finger on the outside your upper lip for 30 seconds to make tablet stick to gums. Leave in place and allow table to dissolve naturally.

If tablet becomes detached anytime over the first 6 hours after original placement, repeat these steps. You can drink liquids but do not brush your teeth during this time.


The active ingredient in Sitavig is Acyclovir.


Let your doctor know of any history of gum disease or other mouth health ailments before starting on Sitavig 50mg

It may be necessary to postpone vaccinations and immunizations while you are using the Sitavig Buccal tablet to get rid of a cold sore

Do not crush, chew, suck, or swallow the tablets

Medication will work best when applied at the very firs sign of a cold sore developing


Negative drug interactions may occur between Sitavig and other Rx medications, including Aczone, fluticasone, salmeterol, amphetamine, trifarotene topical, alpha-lipoic acid, brimonidine ophthalmic, retapamulin topical, tretinoin topical, amiloride, ammonium lactate topical, minocycline topical, anastrozole, aprepitant, leflunomide, aripiprazole, sulfasalazine, diphenhydramine, finasteride, metformin.

Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Sitavig online.

Side Effects

Sitavig side effects may occur, and some users may experience pain at the application site or a headache. If side effects are experienced you may want to stop use and meet with a doctor again to discuss cold sore treatment alternatives.

Frequently Asked Questions about Sitavig

Why is Sitavig so expensive?

Prescription medications that require development for more unique application methods will be more expensive than standard tablet medication because of the development that is required for them.

How long does Sitavig take to dissolve?

Your Sitavig 50mg tablet should fully dissolve within 5 to 6 hours.

How much Acyclovir to take for a cold sore?

The 50mg tablet is usually all that is required to eliminate cold sores for most people, but in the event that dosage is insufficient for you then your doctor will prescribe a higher one.

Can you take Acyclovir while pregnant?

Pregnant women should only use the Sitavig tablet if their doctor approves it.

Can Acyclovir treat bacterial infection?

No, Acyclovir is an antiviral medication and will only be used to treat viral infections. An antibiotic medication will be needed for treating bacterial infections.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.