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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Sotyktu (Deucravacitinib) is a medication that offers a novel approach in the treatment of moderate-to-severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy. Developed by leading scientists, Sotyktu operates by selectively targeting the TYK2 enzyme, which is involved in the inflammatory process that contributes to the development of psoriasis. Unlike traditional therapies that suppress the entire immune system, Sotyktu specifically modulates the pathological pathways involved in the inflammation, resulting in fewer systemic effects.
Before you buy Sotyktu, it is crucial that you talk to your healthcare provider about potential side effects and Sotyktu price.
| Fact Table | |
|---|---|
| Formula | C22H18F2N8O2S |
| License | FDA approved |
| Bioavailability | High oral bioavailability |
| Legal status | Prescription Drugs |
| Chemical Name | Deucravacitinib |
| Elimination half-life | Approximately 10 hours |
| Dosage (Strength) | 6 mg tablet, orally |
| Pregnancy | Not recommended |
| Brands | Sotyktu |
| Protein binding | High (over 98%) |
| PubChem CID | 129112429 |
| MedlinePlus | Not listed |
| ChEBI | Not available |
| ATC code | Not yet assigned |
| DrugBank | DB15480 |
| KEGG | D11984 |
| Routes of administration | Oral |
Sotyktu is taken orally with or without food, simplifying integration into your daily routine. The standard dosage is one 6 mg tablet per day. It is crucial to follow your healthcare provider's instructions precisely regarding dosage and duration of the treatment.
Active Ingredient: Deucravacitinib.
Sotyktu may increase the risk of infections. Patients should inform their doctor if they have symptoms of an infection, such as fever, sweats, or chills.
Regular liver function tests are recommended as Sotyktu can affect liver enzymes.
Discuss with your healthcare provider if you are pregnant, plan to become pregnant, or are breastfeeding. The effects of Sotyktu on unborn children and nursing infants are not fully known.
Avoid live vaccines during treatment with Sotyktu.
Patients should undergo necessary screenings for tuberculosis and other infections before starting therapy with Sotyktu, as it can exacerbate existing infections.
Sotyktu may interact with other medications, which can alter how it or the other medications work. It is important to tell your healthcare provider about all medications, supplements, and herbs you are currently taking. Some known interactions include CYP450 substrates and vaccines. Inform your healthcare provider of any changes in your medication regimen to ensure there are no adverse interactions.
While Sotyktu provides significant benefits for managing psoriasis, it may cause side effects in some individuals. Common side effects include:
What is Sotyktu?
Sotyktu (deucravacitinib) is an oral medication classified as a selective tyrosine kinase 2 (TYK2) inhibitor. It is designed to modulate immune system activity by inhibiting the TYK2 enzyme, which plays a role in the inflammatory process.
What is Sotyktu used for?
Sotyktu is primarily used for the treatment of moderate to severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy.
Is Sotyktu a biologic?
No, Sotyktu is not a biologic. Biologics are typically derived from living organisms and are usually administered via injection or infusion. Sotyktu, however, is a small molecule drug taken orally.
Is Sotyktu an immunosuppressant?
Yes, Sotyktu functions as an immunosuppressant by inhibiting TYK2, a kinase involved in the immune response. This inhibition helps reduce inflammation and immune system activity that contribute to conditions like psoriasis.
Does Sotyktu cause weight gain?
Weight gain is not commonly reported as a side effect of Sotyktu. However, individual responses to medications can vary, so it's important to monitor any changes and discuss them with a healthcare provider.
How does Sotyktu work?
Sotyktu works by selectively inhibiting TYK2, a key enzyme in the signaling pathways of several cytokines involved in the inflammatory process. By blocking TYK2, Sotyktu reduces the activity of these cytokines, thereby decreasing inflammation and immune response associated with plaque psoriasis.
Does Sotyktu cause hair loss?
Hair loss is not commonly associated with Sotyktu use. If you experience hair loss while taking this medication, consult your healthcare provider to determine the cause and appropriate action.
How long does Sotyktu take to work?
The time it takes for Sotyktu to show results can vary. Some patients may notice improvements within a few weeks, while others may require several months to experience significant benefits. Clinical trials have shown improvement in psoriasis symptoms as early as 16 weeks.
What is the success rate of Sotyktu?
Clinical studies have shown that a significant proportion of patients treated with Sotyktu experience clear or almost clear skin. For instance, in clinical trials, around 50-60% of patients achieved a 75% improvement in their Psoriasis Area and Severity Index (PASI 75) score after 16 weeks of treatment.
Can you drink alcohol with Sotyktu?
There are no specific restrictions against drinking alcohol while taking Sotyktu. However, it is always advisable to consume alcohol in moderation and consult your healthcare provider for personalized advice, as alcohol can affect your overall health and interact with medications.
Why is Sotyktu so expensive?
Sotyktu is expensive due to factors such as the cost of research and development, clinical trials, regulatory approval processes, and manufacturing. Additionally, it is a newer medication with advanced technology, which can contribute to higher pricing.
Who cannot take Sotyktu?
Individuals who should not take Sotyktu include those with a known hypersensitivity to deucravacitinib or any of its components. It is also important for individuals with active serious infections, untreated tuberculosis, or certain other medical conditions to avoid this medication. Always consult a healthcare provider for a full evaluation.
Can you just stop taking Sotyktu?
You should not stop taking Sotyktu abruptly without consulting your healthcare provider. Discontinuing treatment suddenly can lead to a return of symptoms. Your healthcare provider can guide you on the proper way to discontinue the medication if necessary.
