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Steglujan (Ertugliflozin/Sitagliptin)

Prescription requiredOnly Available By Prescription
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

What is STEGLUJAN? ? STEGLUJAN contains 2 prescription diabetes medicines called ertugliflozin (STEGLATRO™) and sitagliptin (JANUVIA®). STEGLUJAN can be used along with diet and exercise to lower blood sugar in adults with type 2 diabetes. ? STEGLUJAN is not for people with type 1 diabetes. ? STEGLUJAN is not for people with diabetic ketoacidosis (increased ketones in your blood or urine). ? If you have had pancreatitis (inflammation of the pancreas) in the past, it is not known if you have a higher chance of getting pancreatitis while you take STEGLUJAN. ? It is not known if STEGLUJAN is safe and effective in children under 18 years of age.

Fact Table
Formula C22H25ClO7, C16H15F6N5O
License US DailyMed, US FDA, EU EMA
Bioavailability ~100%, 87%
Legal status Rx-Only
Chemical Name Ertugliflozin / Sitagliptin
Elimination half-life ~17 hours, 8 to 14 h
Dosage (Strength) 5mg/100mg, 15mg/100mg
Pregnancy Consult Doctor
Brands Steglujan
Protein binding 93.6%, 38%
PubChem CID 44814423, 4369359
MedlinePlus a606023
ChEBI 40237
ATC code A10BK04, A10BH01
DrugBank DB11827, DB01261
KEGG D10313, D08516
Routes of administration By mouth

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