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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Stugeron is a medicine that belongs to a wide class of drugs also known as antihistamines. Like any other antihistamine, Stugeron is known to block histamine receptors (these receptors are found in a lot of body sites, including the brain's vomiting centre). Therefore, Stugeron blocks the histamine receptors found in the patient's vomiting centre, preventing the brain from sending any nerve message that would regularly result in vomiting to the stomach. However, vomiting could be triggered by a lot of stimuli that act at the brain's vomiting centre. This also includes provocative movement (this is the case of Motion sickness in a boat or in a car) and vestibular (inner ear) disorders. This is why Stugeron has be designed not only to treat nausea, but also the vomiting that has been associated with other vestibular disorders (for example Meniere's disease) but also with Motion sickness.
Stugeron is a drug that is able to relieve some other symptoms of the inner ear (vestibular) disorder. These symptoms include tinnitus (also known as ringing in the ear) and vertigo, although it has not been clearly determined how Stugeron works in these cases.
The drug's peak (highest) plasma levels are regularly obtained from 1 to 3 hours after the medicine's intake. Stugeron is known to have a half-life of about 4 hours before it completely disappears from the patient's plasma.
Stugeron is a drug that is known to be completely metabolised. It is thought that 1/3 of the drug's metabolites should be eliminated through urination while the other two thirds through the faeces.
Stugeron tablets may cause epigastric distress; taking it after meals may diminish gastric irritation.
Motion Sickness: (Forte - 75mg): As with other antihistamines, cinnarizine may cause epigastric distress; taking it after meals may diminish gastric irritation.
Adults and children over the age of 12 years: Peripheral circulatory disorders: 2-3 x 25 mg tablets three times daily.
Adults: 25 mg may be taken 2 hours before the start of the journey and 12,5 mg to 25 mg may be repeated every 8 hours during the journey when necessary.
Children 8 to 12 years: 12,5 mg (half a tablet) three times daily when necessary.
Children 5 to 7 years: 6,25 mg three times daily when necessary.
Adults and children over the age of 12 years: Peripheral circulatory disorders: 2 to 3 capsules of 75 mg daily. Disorders of balance: 1 capsule of 75 mg daily.
The maximum recommended dosage should not exceed 225 mg (3 capsules) daily - if necessary the dosage may be divided over 2 or 3 intakes per day. As the effect of cinnarizine on vertigo is dose dependant, the dosage should be increased progressively.