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Synvisc - One (Hylan)

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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Synvisc-One (Hylan) is a viscosupplement injection designed to treat knee osteoarthritis. It acts as a lubricant and shock absorber in the knee joint, mimicking the natural synovial fluid. Synvisc-One provides relief from pain and improves joint mobility, offering patients a non-surgical option to manage their osteoarthritis symptoms.

Before you buy Synvisc-One injection, it is crucial that you talk to your healthcare provider about potential side effects and Synvisc-One injection cost.

Fact Table
Formula Not applicable (mixture of hylan polymers derived from chicken combs)
License FDA approved
Bioavailability Not applicable (intra-articular injection)
Legal status Prescription only
Chemical Name Hylan G-F 20
Elimination half-life Approximately 1-2 weeks in the synovial fluid
Dosage (Strength) Single intra-articular injection of 6 mL
Pregnancy advice Not classified; consult healthcare provider
Brands Synvisc-One
Protein binding Not applicable
PubChem CID Not listed
MedlinePlus Not listed
ChEBI Not listed
ATC code M09AX05
DrugBank Not listed
KEGG Not listed
Routes of administration Intra-articular

Buy Synvisc - One (Hylan) online from online Canadian Pharmacy |


Before receiving Synvisc-One, consult with an orthopedic specialist or rheumatologist to determine if it's the right treatment for you.

The area around the knee will be cleaned and may be numbed.

Synvisc-One dosage is injected directly into the knee joint.

After the injection, it's advisable to avoid strenuous activities for about 48 hours. Light activities and walking can be resumed shortly after the procedure.


Active Ingredient: Hylan G-F 20 (a derivative of hyaluronic acid).


Do not use Synvisc-One if you have a known allergy to hyaluronan products.

Avoid activities that put excessive strain on the knee for at least 48 hours post-injection.

Inform your doctor if you have infections or skin diseases around the injection site.

Synvisc-One is exclusively authorized for application in the knee.

If swelling or pain persists or increases after the injection, seek medical attention.


Drugs that may have interactions with Synvisc-One include topical benzalkonium chloride, topical cetylpyridinium.

Side Effects

Common side effects of this medication may include pain or swelling at the injection site, fluid buildup in the knee, heat sensation in the treated knee, mild pain, or stiffness.

Frequently Asked Questions about Synvisc-One

Does Synvisc-One really work?

Yes, many patients have reported significant pain relief and improved mobility after receiving Synvisc-One injections.

Is Synvisc-One a steroid?

No, Synvisc-One is not a steroid. It's a viscosupplement made from a derivative of hyaluronic acid.

How long does Synvisc-One last?

The effects of Synvisc-One can last up to six months. However, the duration of relief can vary among individuals.

How many Synvisc-One injections can I have?

Typically, one injection of Synvisc-One is given, but the number of injections can be determined based on individual needs and a doctor's recommendation.

How often can Synvisc-One be given?

While one injection can provide relief for up to six months, subsequent injections can be considered based on your doctor's advice and your specific needs.

What is Synvisc-One made of?

Synvisc-One is made of Hylan G-F 20, a derivative of hyaluronic acid, which mimics the natural synovial fluid in the knee.

What is the difference between Synvisc and Synvisc-One?

The primary difference is the treatment regimen. Synvisc requires three injections given one week apart, while Synvisc-One provides the same treatment benefits with a single injection.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.