Synvisc - One (Hylan)
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Fact Table
| Fact Table | |
|---|---|
| Formula | Not applicable (mixture of hylan polymers derived from chicken combs) |
| License | FDA approved |
| Bioavailability | Not applicable (intra-articular injection) |
| Legal status | Prescription only |
| Chemical Name | Hylan G-F 20 |
| Elimination half-life | Approximately 1-2 weeks in the synovial fluid |
| Dosage (Strength) | Single intra-articular injection of 6 mL |
| Pregnancy advice | Not classified; consult healthcare provider |
| Brands | Synvisc-One |
| Protein binding | Not applicable |
| PubChem CID | Not listed |
| MedlinePlus | Not listed |
| ChEBI | Not listed |
| ATC code | M09AX05 |
| DrugBank | Not listed |
| KEGG | Not listed |
| Routes of administration | Intra-articular |
Synvisc-One (Hylan) is a viscosupplement injection designed to treat knee osteoarthritis. It acts as a lubricant and shock absorber in the knee joint, mimicking the natural synovial fluid. Synvisc-One provides relief from pain and improves joint mobility, offering patients a non-surgical option to manage their osteoarthritis symptoms.
Before you buy Synvisc-One injection, it is crucial that you talk to your healthcare provider about potential side effects and Synvisc-One injection cost.
Directions
Before receiving Synvisc-One, consult with an orthopedic specialist or rheumatologist to determine if it's the right treatment for you.
The area around the knee will be cleaned and may be numbed.
Synvisc-One dosage is injected directly into the knee joint.
After the injection, it's advisable to avoid strenuous activities for about 48 hours. Light activities and walking can be resumed shortly after the procedure.
Ingredients
Active Ingredient: Hylan G-F 20 (a derivative of hyaluronic acid).
Cautions
Do not use Synvisc-One if you have a known allergy to hyaluronan products.
Avoid activities that put excessive strain on the knee for at least 48 hours post-injection.
Inform your doctor if you have infections or skin diseases around the injection site.
Synvisc-One is exclusively authorized for application in the knee.
If swelling or pain persists or increases after the injection, seek medical attention.
Interactions
Drugs that may have interactions with Synvisc-One include topical benzalkonium chloride, topical cetylpyridinium.
Side Effects
Common side effects of this medication may include pain or swelling at the injection site, fluid buildup in the knee, heat sensation in the treated knee, mild pain, or stiffness.
Frequently Asked Questions about Synvisc-One
Does Synvisc-One really work?
Yes, many patients have reported significant pain relief and improved mobility after receiving Synvisc-One injections.
Is Synvisc-One a steroid?
No, Synvisc-One is not a steroid. It's a viscosupplement made from a derivative of hyaluronic acid.
How long does Synvisc-One last?
The effects of Synvisc-One can last up to six months. However, the duration of relief can vary among individuals.
How many Synvisc-One injections can I have?
Typically, one injection of Synvisc-One is given, but the number of injections can be determined based on individual needs and a doctor's recommendation.
How often can Synvisc-One be given?
While one injection can provide relief for up to six months, subsequent injections can be considered based on your doctor's advice and your specific needs.
What is Synvisc-One made of?
Synvisc-One is made of Hylan G-F 20, a derivative of hyaluronic acid, which mimics the natural synovial fluid in the knee.
What is the difference between Synvisc and Synvisc-One?
The primary difference is the treatment regimen. Synvisc requires three injections given one week apart, while Synvisc-One provides the same treatment benefits with a single injection.
