Tasigna (Nilotinib Hydrochloride)

Prescription Required
Brand
Dose Size & Price Qty
75mg
150mg
200mg
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Fact Table

Fact Table
Formula C28H22F3N7O
License US DailyMed, EU EMA
Bioavailability 30%
Legal status Rx-Only
Chemical Name Nilotinib
Elimination half-life 15-17 hours
Dosage (Strength) 75mg, 200mg
Pregnancy Not safe
Brands Tasigna
Protein binding 98%
PubChem CID 644241
MedlinePlus a608002
ChEBI 52172
ATC code L01EA03
DrugBank DB04868
KEGG D08953
Routes of administration By mouth

TASIGNA capsules is used to treat a type of leukemia called Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML) in adult patients who: are no longer benefitting from another treatment, including treatment with imatinib; have taken other treatments and cannot tolerate them

Directions

Take TASIGNA: -At least 2 hours after eating any food, and
-After taking TASIGNA, wait at least 1 hour before eating any food
-Swallow the capsules whole with water.
-Do NOT open the capsules.
-Avoid grapefruit, grapefruit juice, and any supplement containing grapefruit extract while taking TASIGNA. Food and grapefruit products increase blood levels of TASIGNA in your body.
-If a dose is missed, take the next dose as scheduled. Do not take a double dose to make up for the forgotten capsules.

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