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Fact Table
| Fact Table | |
|---|---|
| Formula | C25H28N8O2 |
| License | FDA and EMA approved |
| Bioavailability | ~30% |
| Legal status | Prescription Drug |
| Chemical Name | 8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butyn-1-yl)-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-3,7-dihydro-1H-purine-2,6-dione |
| Elimination half-life | ~12 hours (terminal half-life up to 120 hours due to receptor binding) |
| Dosage (Strength) | 5mg oral tablets |
| Pregnancy | Consult Doctor (Limited human data; use only if clearly needed) |
| Brands | Tradjenta |
| Protein binding | ~70-99% |
| PubChem CID | 10096344 |
| MedlinePlus | a611019 |
| ChEBI | 688958 |
| ATC code | A10BH05 |
| DrugBank | DB08882 |
| KEGG | D09515 |
| Routes of administration | By mouth |
Tradjenta is a blood sugar control medication used for treatment of Type 2 diabetes. Linagliptin is dipeptidyl peptidase-4 inhibitor drug that increases levels of GLP-1 and GIP peptides so that the pancreas produces more insulin and limits glucagon hormone. Patients taking Tradjenta 5mg will typically be able to lower their A1C scores although it can take several weeks on the medication to start seeing these results. You can buy Tradjenta with a prescription here at Canpharm.
Directions
Standard dosage for Tradjenta is to take 1 tablet 1x daily with or without food. It is best to take this medication at around the same time each day.
Ingredients
The active ingredient in Tradjenta is Linagliptin
Cautions
Let your doctor know of any history of heart or kidney failure, high triglycerides, pancreatitis, gallstones, or alcohol use disorder before starting on Tradjenta generic
Do not exceed 1x-daily dosage regulations unless indicated in prescription
Women who are pregnant or breastfeeding should only use this medication if a doctor approves it
Be aware of medication expiry date
Interactions
Negative drug interactions may occur between Tradjenta and other Rx or OTC medications, including amlodipine, atorvastatin, carvedilol, apixaban, furosemide, gabapentin, glimepiride, glipizide, hydrochlorothiazide, empagliflozin, levothyroxine, lisinopril, losartan, metformin, metoprolol, omeprazole, pantoprazole, prednisone, rosuvastatin, simvastatin, spironolactone, tamsulosin, and tramadol.
Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Tradjenta online.
Side Effects
Tradjenta side effects may occur and some users may experience runny nose, nasal congestion, diarrhea, sore throat, or cough. If side effects are seen you may want to discontinue use and meet with a doctor again to discuss Type 2 diabetes treatment medication alternatives.
Frequently Asked Questions about Tradjenta (Linagliptin)
Why is Tradjenta so expensive?
Tradjenta (linagliptin) is expensive because it is a brand-name medication that is still under patent protection. This means that no generic version is available yet, and the cost is typically higher due to lack of competition in the market.
What are the bad side effects of Tradjenta?
Some potential side effects of Tradjenta include upper respiratory tract infections, headache, diarrhea, and in rare cases, pancreatitis or severe allergic reactions. Always discuss any concerning symptoms with your doctor.
Is Tradjenta bad for kidneys?
Tradjenta is generally considered safe for people with mild to moderate kidney impairment, but it is important to consult with your doctor if you have kidney issues. It is not recommended for individuals with severe kidney impairment.
How long does it take for Tradjenta to work?
Tradjenta starts working to lower blood sugar levels within a few hours, but the full effect may take a few weeks to see. It helps improve glycemic control over time when combined with diet and exercise.
Can you take Tradjenta and Ozempic together?
Yes, Tradjenta and Ozempic (semaglutide) can be taken together under a doctor's supervision. They work through different mechanisms, and combining them can help improve blood sugar control in people with type 2 diabetes.
Can I take Tradjenta at night?
Yes, Tradjenta can be taken at any time of day, with or without food. The most important thing is to take it consistently at the same time each day to help manage blood sugar levels.
Can Tradjenta be taken twice a day?
No, Tradjenta is typically taken once daily, as directed by your healthcare provider. Do not take more than the prescribed dose.
Can you take Tradjenta and Jardiance together?
Yes, Tradjenta (linagliptin) and Jardiance (empagliflozin) can be used together to manage blood sugar levels in type 2 diabetes. However, this combination should be done under the supervision of a healthcare provider.
Can Tradjenta cause weight gain?
No, Tradjenta is generally weight-neutral, meaning it does not cause significant weight gain. In fact, some people may experience slight weight loss as part of their overall diabetes management plan.
Does Tradjenta affect blood pressure?
Tradjenta has minimal effect on blood pressure, but it is not typically prescribed to treat blood pressure issues. It’s important to monitor blood pressure regularly, especially when managing type 2 diabetes.
