Trelegy Ellipta (Fluticasone Furoate / Umeclidinium / Vilanterol Trifenatate)

Prescription Required
Brand
Dose Size & Price Qty
100 / 62.5 / 25mcg (same as 92 / 55 / 22mcg) (30 doses / inhaler)
200 / 62.5 / 25mcg (same as 184 / 55 / 22mcg) (30 doses / inhaler)
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Fact Table

Fact Table
Formula C80H96Cl2F3N2O13S+
License EU EMA, US FDA
Bioavailability 15.2%
Legal status RX Only
Chemical Name Fluticasone Furoate / Umeclidinium / Vilanterol Trifenatate
Elimination half-life 15.1 hours
Dosage (Strength) 92/55/22mcg (100/62.5/25mcg) (30 doses/inhaler), 200/62.5/25mcg (30 doses/inhaler)
Pregnancy Consult a doctor
Brands Trelegy Ellipta
Protein binding Greater than 99.6%
PubChem CID 122403924
MedlinePlus a618017
ChEBI -
ATC code R03AL08
DrugBank DB08906, DB09076, DB09082
KEGG D11035
Routes of administration Topical

Trelegy Ellipta is a prescription for treating chronic obstructive pulmonary disease (COPD). It combines fluticasone furoate, umeclidinium, and vilanterol to reduce inflammation, relax airway muscles, and improve breathing. It is inhaled once daily using an Ellipta inhaler.

Before you plan to buy Trelegy Ellipta for treating COPD, it is crucial to understand its effectiveness, potential side effects, and Trelegy Ellipta price.

What is COPD?

COPD, or chronic obstructive pulmonary disease, is a chronic lung condition characterized by persistent airflow limitation that makes breathing difficult. It includes chronic bronchitis and emphysema. While COPD cannot be cured, treatments are available to manage symptoms and slow down its progression.

Directions

Take Trelegy Ellipta inhalation once daily at the recommended dose.

Use the inhaler at the same time each day to maximize its benefits.

Open the inhaler only when you're ready to use it, as each open-close action prepares a dose.

Rinse your mouth with water after inhaling to reduce the risk of thrush.

If you miss a dose, skip it, and continue your regular schedule. Avoid doubling the dose.

Dispose of any remaining medication in the inhaler after six weeks or as directed.

Ingredients

Fluticasone Furoate, Umeclidinium, and Vilanterol are the active ingredients.

Cautions

Inform your doctor of any allergies, including fluticasone, umeclidinium, or vilanterol.

Discuss your medical history, especially infections, heart problems, high blood pressure, bone loss, eye problems, difficulty urinating, seizures, overactive thyroid, diabetes, or liver disease.

This medication may increase the risk of infections or worsen existing infections.

If you have recently switched from oral corticosteroids or used high doses of this product, it may affect your body's response to physical stress.

Carry a warning card or medical ID bracelet indicating your use of corticosteroid medications.

Long-term use of this medication may temporarily slow down a child's growth. Regular check-ups are important.

Discuss the use of this medication during pregnancy with your doctor.

Interactions

Trelegy Ellipta, which contains fluticasone, umeclidinium, and vilanterol, has a wide range of drug interactions and disease interactions. There are 513 known drug interactions categorized as 53 major, 442 moderate, and 18 minor interactions. It is important to review these interactions, especially if you are taking other medications. Additionally, Trelegy Ellipta interacts with 13 different diseases.

Side Effects

Common side effects of the Trelegy Ellipta inhaler may include an upper respiratory tract infection, pneumonia, headache, back pain, joint pain, bone fractures, muscle spasms, thrush, voice changes, cough, sore throat, sinusitis, or a urinary tract infection.


Frequently Asked Questions about Trelegy Ellipta


Is Trelegy Ellipta a steroid?

Yes, Trelegy Ellipta contains a steroid component. It is a combination medication that contains three active ingredients: fluticasone furoate, umeclidinium, and vilanterol. Fluticasone furoate is a corticosteroid, which means it has anti-inflammatory properties.


What tier drug is Trelegy Ellipta?

Trelegy Ellipta is considered a higher-tier or specialty medication. It is typically classified as a Tier 3 drug, which means it may have higher out-of-pocket costs than lower-tier medications.


Can Trelegy Ellipta cause weight gain?

Although not very common, weight gain is a possible side effect of Trelegy Ellipta. Since individual responses to medications can vary, some people may experience weight gain while others may not.


How long does it take for Trelegy Ellipta to work?

The time it takes for Trelegy Ellipta to work can vary between individuals. Some people may notice improvements in their symptoms within a few days or weeks, while others may require several weeks or months.


How many doses in Trelegy Ellipta?

A single Trelegy Ellipta inhaler contains 30 doses. Each dose is intended for inhalation once daily, meaning one inhaler will last approximately one month of use.


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