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Treximet (Naproxen/Sumatriptan)

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Top Generic choice

What is Generic?

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Treximet is a prescribed medication used for relieving symptoms associated with migraines. It can be used either as a standalone treatment or in combination with other medications. Treximet falls under the category of NSAIDs and Serotonin 5-HT-Receptor Agonists. However, its safety and effectiveness in children under the age of 12 have not been established.

When considering treatment options for migraines, it's important to consider factors such as effectiveness, potential side effects, and the Treximet cost.

Fact Table
Formula C32H40N3NaO9S
License US FDA, EU EMA, US DailyMed
Bioavailability 15%(Sumatriptan), 95%(Naproxen)
Legal status Rx-Only
Chemical Name Naproxen/Sumatriptan
Elimination half-life 2.5 hours(Sumatriptan), 12–17 hours (Naproxen)
Dosage (Strength) 85mg/500mg (Generic)
Pregnancy Consult a healthcare provider
Brands Treximet
Protein binding 14–21%(Sumatriptan), 99%(Naproxen)
PubChem CID 23709079
MedlinePlus a601116
ChEBI 10650
ATC code N02CC01, G01AE10
DrugBank DB00669
KEGG D11577
Routes of administration By mouth

Buy Treximet (Naproxen/Sumatriptan) online from online Canadian Pharmacy |


Take Treximet Generic exactly as instructed by your doctor.

Swallow Treximet tablets whole with water or any other liquid, with or without food.

If you don't experience any relief after the first dose, don't take a second dose without consulting your doctor.

For children aged 12 to 17, it's uncertain if taking more than one dose within 24 hours is safe and effective. Discuss with your doctor what to do if your headache persists or comes back.


The active ingredients in Treximet are Naproxena and Sumatriptan.


Do not use this medication if you are allergic to naproxen or sumatriptan.

Avoid using this medicine before or after heart bypass surgery.

Naproxen may cause stomach or intestinal bleeding, especially in older adults, which can be fatal.

Avoid using Treximet in combination with other migraine headache medications or ergot medicines within a 24-hour period before or after taking them.

Inform your doctor about your medical history, including heart problems, high blood pressure, high cholesterol, diabetes, smoking, asthma, epilepsy or seizure disorder, and liver or kidney disease.


Please inform your doctor about all the medications you are currently taking as Treximet could potentially have interactions with blood thinners, lithium, methotrexate, probenecid, diuretics, steroids, aspirin, other NSAIDs, ACE inhibitors, beta-blockers, or antidepressants.

Side Effects

Common side effects that adults may experience with Treximet include:

  • Dizziness
  • Sleepiness
  • Nausea
  • Chest pain or discomfort
  • Discomfort in the throat, neck, or jaw area
  • Sensations of tingling or loss of feeling in the hands or feet
  • Dry mouth
  • Indigestion

These side effects are typically temporary and tend to resolve within a few days or weeks. Before you buy Treximet, it is recommended to consult with your doctor to understand your dosage and the potential side effects you may experience.

Frequently Asked Questions about Treximet

How long does Treximet stay in your system?

Treximet can stay in your system for a few days after the last dose. The half-life of sumatriptan is about 2-2.5 hours, and for naproxen, it is approximately 12-17 hours.

Is there a generic for Treximet?

Yes, there is a generic available for Treximet. You can get the best price on Treximet online if you buy it from Canada or Canpharm.

Is Treximet a narcotic?

No, Treximet is not a narcotic. It is a combination medication used for migraines. Treximet contains sumatriptan and naproxen, which are not narcotics.

Does Treximet make you sleepy?

Treximet may cause drowsiness in some people. It is one of the side effects of this medication. If you feel sleepy after taking it, avoid activities that require alertness.

How often can I take Treximet?

You can use Treximet or other migraine medications for a maximum of 9 days per month. Using them more often can make your headaches worse, resulting in medication overuse headaches.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.