Vepesid (Etoposide)
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Description
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Fact Table
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| Formula | C29H32O13 |
| License | FDA approved |
| Bioavailability | 25–75% |
| Legal status | Prescription only |
| Chemical Name | 4'-Demethylepipodophyllotoxin 9-[4,6-O-(R)-ethylidene-ß-D-glucopyranoside] |
| Elimination half-life | 4–11 hours |
| Dosage (Strength) | 50mg, 100mg capsules; 20mg/mL injection |
| Pregnancy | Consult doctor (Category D - positive evidence of risk) |
| Brands | Vepesid, Toposar, Etopophos |
| Protein binding | 97% |
| PubChem CID | 36462 |
| MedlinePlus | a682621 |
| ChEBI | 4911 |
| ATC code | L01CB01 |
| DrugBank | DB00773 |
| KEGG | D07916 |
| Routes of administration | By mouth, intravenous |
Vepesid is a cancer treatment medication most commonly prescribed for testicular or small cell lung cancer treatment. Etoposide is a mitotic inhibitor medication that slows the growth of cancer cells and improves the chances of favorable outcomes when treating these types of cancer. Vepesid capsules are usually taken on a specific dose cycle that is repeated every 3 to 4 weeks. You can buy Vepesid with a prescription here at Canpharm.
Directions
Standard dosage for Vepesid oral is 50 to 100 mg/m2 IV over 30 to 60 minutes 1x daily on days 1 throu5 5 and then 100 mg/m2 IV over 30 to 60 minutes once a day on days 1, 3, and 5. This dosage cycle usually repeats3 to 4 weeks and all of this will be very clearly detailed in your prescriptions along with the discussions with your doctor in advance of beginning your cancer treatment.
Ingredients
The active ingredient in Vepesid is Etoposide
Cautions
Let your doctor know of any history of liver or kidney disease, low red or white blood cell counts, poor heart health, or previous chemotherapy or radiation treatments before starting on Vepesid
Use of this medication may make you more susceptible to infections or make existing infections worse. Avoid people who may have an infection while you are using Vepesid
Added risk of bruising or bleeding due to this medication means users should be cautious about certain objects and activities
Use of this medication may make you dizzy or drowsy. It may be advisable to avoid driving or operating machinery while using Vepesid
You should strictly limit or abstain from alcohol while taking this medication because of the increased risk of stomach bleeding
Older adults and children may be more susceptible to side effects from Vepesid capsules
Use of this medication can affect fertility for either gender
Women who are breastfeeding should not use Vepesid unless their doctor approves it
Interactions
Negative drug interactions may occur between Vepesid and other Rx or OTC medications, including Adriamycin, Aranesp, Ativan, Bactrim, Celebrex, Cipro, Co-trimoxazole, Colace, Compazine, Cytoxan, Demerol, Eliquis, Keppra, Neulasta, Neupogen, Protonix, Rituxan, Taxol, Xanax, Zofran, and Zometa. Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Vepesid online.
Side Effects
Vepesid side effects may occur, and some users may experience nausea, vomiting, diarrhea, dizziness, tiredness, weakness, taste changes, appetite loss, and pain or redness at the injection site. If side effects are seen you may want to discontinue use and meet with a doctor again to discuss cancer treatment medication alternatives and a pharmacist for a lower Vepesid cost.
Frequently Asked Questions about Vepesid (Etoposide)
What is the drug Vepesid used for?
Vepesid (etoposide) is a chemotherapy medication used to treat various cancers, including small cell lung cancer, testicular cancer, and sometimes other types of cancer as part of combination therapy.
What is a common side effect of etoposide?
A common side effect of etoposide is low blood cell counts (myelosuppression), which can increase the risk of infections, bleeding, or anemia.
What foods should you avoid when taking etoposide?
While there are no strict food restrictions, avoid alcohol and grapefruit or grapefruit juice, as they can interfere with the metabolism of the drug. Also, eat foods that are gentle on the stomach if nausea occurs.
Is etoposide well tolerated?
Etoposide is generally well tolerated, but side effects such as fatigue, nausea, hair loss, and myelosuppression are common. The tolerability varies by individual and dosage.
How long does etoposide stay in the body?
Etoposide has a half-life of about 4–11 hours, meaning it can take around 1–2 days for most of the drug to be eliminated from the body. However, traces may remain longer.
What is the maintenance of etoposide?
Etoposide is typically given as part of a chemotherapy regimen in cycles, with specific dosages and schedules depending on the type and stage of cancer. It is not typically used as a maintenance therapy but as part of active treatment.
What are the benefits of etoposide?
The benefits of etoposide include its ability to slow or stop the growth of cancer cells, shrink tumors, and improve survival rates in combination with other treatments for certain cancers. It is a proven and effective component of many cancer treatment protocols.
