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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Xarelto is a prescription blood clot prevention medication that reduces the risk of heart attack, embolism, or stroke resulting from blood clots when atrial fibrillation (irregular heartbeat) occurs. It is most commonly prescribed when individuals are set to have hip or knee replacement surgery, and the risk of such events is at its highest accordingly. Rivaroxaban is an anticoagulant that prevents blood cells from being able to clump together and form clots. Xarelto may also be prescribed to treat DVT (deep vein thrombosis), and in rarer instances, it is a medication for blood clot prevention following the Fontan procedure for children.
You can buy Xarelto with a prescription, and if you want to get the best deal on medication, consider purchasing it online from Canada and Canpharm.
Blood clots are little gel-like plugs. They usually happen when you get injured, shutting off your wounds and preventing bleeding. But sometimes blood clots form in places they shouldn't and block proper blood flow. The clot doesn't dissolve naturally and can seriously injure you by causing heart attacks, strokes, and other medical problems. Different treatments for blood clots include anticoagulants (blood thinners) and special compression socks.
| Fact Table | |
|---|---|
| Formula | C19H18ClN3O5S |
| License | US FDA, EU EMA, US DailyMed |
| Bioavailability | 80–100% |
| Legal status | Rx-Only |
| Chemical Name | Rivaroxaban |
| Elimination half-life | 5–9 hours |
| Dosage (Strength) | 2.5mg, 10mg, 15mg, 20mg |
| Pregnancy | Consult Doctor |
| Brands | Xarelto |
| Protein binding | 92% to 95% |
| PubChem CID | 6433119 |
| MedlinePlus | a611049 |
| ChEBI | 68579 |
| ATC code | B01AF01 |
| DrugBank | DB06228 |
| KEGG | D07086 |
| Routes of administration | By mouth |
Xarelto and any generic for Xarelto will come is 2.5mg, 5mg, 10mg and 20mg strengths.
Standard Xarelto dosage for DVT prevention or to prevent a pulmonary embolism is 15 mg twice each day for 21 days. Then the dose is lowered to 20 mg once each day.
Standard dosage for blood clot prevention after surgery is 10mg taken once daily for a duration determined by your doctor.
Atrial fibrillation: 20mg once daily.
Fontan procedure: Xarelto dosage is based on the child’s body weight, and this will be clearly indicated in the prescription as well as made clear in discussion with your doctor prior to surgery.
The active ingredient in Xarelto is Rivaroxaban.
Let your doctor know of any history of high blood pressure (hypertension), hemorrhagic stroke, stomach bleeding or ulcers, genetic spinal defect, spinal taps or having an epidural anaesthesia, liver or kidney problem, or antiphospholipid syndrome (sticky blood disease / Hughes’ disease) before starting on Xarelto.
Any surgery requiring anaesthesia may require you to stop using Xarelto for a period of time before the surgery.
Use Xarelto when pregnant only if approved to do so by your doctor.
Keep medication away from moisture and heat.
Negative drug interactions may occur between Xarelto and other Rx or OTC medications, including amlodipine, aspirin, atorvastatin, carvedilol, furosemide, gabapentin, levothyroxine, lisinopril, losartan, metformin, metoprolol, omeprazole, pantoprazole, potassium chloride, prednisone, tamsulosin, tramadol, cyanocobalamin, cholecalciferol.
Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Xarelto online.
Side effects from Xarelto may occur, and some users may have pain in arms or legs, muscle pain, or itching. If side effects are seen you may want to stop use and meet with your doctor again to discuss blood clot prevention medication alternatives.
What is Xarelto Used for?
Xarelto is a prescription medication used to prevent and treat blood clots that form inside your body. Blood clots don't naturally form inside your body and can cause you harm. Xarelto works by preventing new blood clots from forming, reducing the risk of strokes and heart attacks in people with heart conditions like atrial fibrillation (irregular heartbeat), and preventing deep vein thrombosis (blood clots in legs) and pulmonary embolisms (blood clots in lungs).
How Long Does Xarelto Stay in Your System?
Xarelto takes up to four hours to work and stays in your system for a few days (usually 1-3). This depends on metabolism, dosage, kidney function, and interactions with other medications. It's best to find the exact details from the doctor who prescribes the medication. A common medication used for blood clots is warfarin, which takes almost double the time to work and stays in the body for up to one week, making it a good option to buy Xarelto if you have surgery.
Is Xarelto a Blood Thinner?
Yes, Xarelto is classified as a blood thinner. Specifically, it is an anticoagulant, one of the two types of blood thinners. Xarelto doesn't break up blood clots but prevents new ones from forming by blocking enzymes that assist in the clotting process. This helps blood flow smoothly through your veins and arteries.
What Happens if You Miss a Dose of Xarelto?
Generally, take your Xarelto dosing once a day with your evening meal (sometimes twice if your doctor recommends it for DVT). If you miss taking it, it is important to do so as soon as you remember, except if it's close to the time of your next dose. It is not recommended to take Xarelto twice to make up for the missed one. You can resume taking your next dose at your scheduled time.
Is Xarelto an Anticoagulant?
Yes, Xarelto is classified as an anticoagulant. This is one of the two types of blood thinners, the other being antiplatelets. The way anticoagulants work is they keep your blood from clotting, and Xarelto, in particular, does this by blocking an enzyme that is essential to the clotting process.
Does Xarelto Make You Tired?
While Xarelto does not tire you directly, it can cause bleeding (its most common potential side effect). In rare cases, this bleeding will not stop, and excessive blood loss can lead to lower blood pressure and symptoms of fatigue.
How Long to Hold Xarelto Before Surgery?
It is generally recommended that you stop taking Xarelto 1-2 days before surgery (with 24 hours being the minimum). There may be exceptions, but this needs to be discussed with your doctor.
