Xeljanz (Tofacitinib)

Prescription Required
Brand
Dose Size & Price Qty
5mg
10mg
Generic
Dose Size & Price Qty
5mg
10mg
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Fact Table

Fact Table
Formula C16H20N6O
License FDA approved in 2012
Bioavailability 74%
Legal status Prescription only
Chemical Name Tofacitinib
Elimination half-life 3 hours
Dosage (Strength) 5 mg and 10 mg tablets
Pregnancy Use only if clearly needed and the benefit outweighs the risk
Brands Xeljanz, Xeljanz XR
Protein binding 40%
PubChem CID 9926791
MedlinePlus a613042
ChEBI CHEBI:71230
ATC code L04AA29
DrugBank DB08895
KEGG D09966
Routes of administration Oral

Xeljanz is an anti-inflammatory medication available by prescription and used for treatment of different conditions caused by inflammation. These include rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis among others. Tofacitinib works by disrupting JAK (Janus Kinus) pathways in cells to reduce the body’s inflammatory response. It is often prescribed for those who have not had success with methotrexate or other arthritis medications. Buy Xeljanz from Canada and Canada and get the lowest Xeljanz cost on it.

Directions

Standard Xeljanz dosage guidelines are as follows:

Psoriatic arthritis / rheumatoid arthritis - either 5mg orally twice a day (immediate release) or 11mg orally once a day (extended release)

Ulcerative colitis: therapeutic dose of 10 mg orally 2 times a day for initial 8 weeks; Maintenance dose: 5 mg orally 2 times a day

Ingredients

The active ingredient in Xeljanz is Tofacitinib.

Cautions

Let your doctor know any history of liver or kidney disease or renal failure, tuberculosis, heart problems, lung disease, blood clots, chronic infections, HIV, ulcers, diverticulitis, or diabetes before starting on Xeljanz

It may be necessary to postpone or temporarily discontinue use of Xeljanz XR if you are planning to take a vaccine. Discuss with your doctor before discontinuing use.

Do not take Xeljanz XR is you are pregnant or planning to become pregnant unless your doctor approves it

Interactions

Negative drug interactions may occur between Xeljanz and other Rx medications, including amlodipine, atorvastatin, duloxetine, gabapentin, hydroxychloroquine, levothyroxine, lisinopril, losartan, pregabalin, meloxicam, methotrexate, omeprazole, pantoprazole, hydroxychloroquine, prednisone, tramadol, and trazodone. Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Xeljanz online.

Side Effects

Xeljanz side effects may occur, and some people may experience diarrhea, headache, upper respiratory infections like the common cold, rash, or elevated blood cholesterol levels. If side effects are experienced it may be best to stop use and meet with a doctor again to discuss prescription anti-inflammatory medication alternatives.


Remember, these are not exhaustive lists, and it's important to consult with a healthcare professional for personalized advice and guidance. If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit www.fda.gov/MedWatch or call 1-800-FDA-1088


Frequently Asked Questions about Xeljanz


Is Xeljanz a biologic?

No, Xeljanz is not a biologic medication.


Does Xeljanz cause weight gain?

Weight gain is not among the common side effects from using this medication. If you are gaining weight at the same time as you are using Xeljanz then the weight gain is not likely due to the medication.


Is Xeljanz an immunosuppressant?

No, Xeljanz is not an immunosuppressant. It is a JAK (Janus Kinase) inhibitor class medication.


Do Xeljanz side effects go away?

For most users, the side effects from using this medication are temporary, but some people may be more likely to have them last longer based on their physiology or overall health. If side effects continue and are unbearable, you may want to stop using Xeljanz and discuss this with your doctor.


Does Xeljanz cause hair loss?

Hair loss is not among the common side effects from using this medication. If you are losing hair at the same time as you are using Xeljanz, then the hair loss is not likely due to the medication.


How long does it take Xeljanz to work?

Most users will experience relief from inflammation pain and/or immobility within 3-6 hours of taking a dose of this medication.


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