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Only Available By Prescription
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Zepbound is an injectable medication that, along with a reduced-calorie diet and increased physical activity, is used for chronic weight management in obese or overweight adults who have one or more weight-related comorbid conditions, such as high blood pressure, dyslipidemia, type 2 diabetes, obstructive sleep apnea, or cardiovascular disease. Zepbound is available by prescription only.
Zepbound is supplied as single-dose injectable pens. The pens are available in 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, or 15 mg per 0.5 mL.
| Fact Table | |
|---|---|
| Formula | C225H348N48O68 |
| License | US DailyMed |
| Bioavailability | 80% |
| Legal status | Rx-Only |
| Chemical Name | Tirzepatide |
| Elimination half-life | Five days |
| Dosage (Strength) | 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, or 15 mg per 0.5 mL |
| Pregnancy | Consult Doctor |
| Brands | Zepbound |
| Protein binding | 99% |
| PubChem CID | 156588324 |
| MedlinePlus | a622044 |
| ChEBI | 194186 |
| ATC code | A10BX16 |
| DrugBank | DB15171 |
| KEGG | D11360 |
| Routes of administration | Subcutaneous |
Zepbound should be used as directed by your doctor. Inform your doctor or pharmacist of any questions or concerns you may have about the medication.
Your healthcare provider will determine an appropriate dose for you and will instruct you on the proper administration of Zepbound. Inject your prescribed dose once weekly underneath the skin in the abdomen, thigh, or upper arm. Be sure to rotate your injection sites with each dose.
Storage:
Store Zepbound in the refrigerator between 2°C and 8°C (36°F and 46°F) in its original carton. Avoid freezing the medication.
You may store the pens at 30°C (86°F) or below for up to 21 days. If you choose to store them at room temperature, do not place them back into the refrigerator. Properly dispose of the medication if it has not been used within 21 days of taking it out of the refrigerator.
Keep all medications away from children’s reach.
The ingredient in the type 2 diabetes medication Mounjaro®, tirzepatide, is the active ingredient in Zepbound.
Patients with a personal or family history of medullary thyroid carcinoma or patients with Multiple Endocrine Neoplasia syndrome type 2 should avoid using Zepbound.
Patients who are allergic to tirzepatide or to any of the excipients in Zepbound should also avoid using the medication.
Zepbound contains the following FDA Boxed Warning:
Common side effects of Zepbound include nausea, diarrhea, vomiting, constipation, abdominal pain, dyspepsia, injection site reactions, fatigue, hypersensitivity reactions, eructation, hair loss, and gastroesophageal reflux disease. Other side effects can also occur, so be sure to inform your doctor of any worrisome or persistent side effects.
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What is Zepbound?
Zepbound is a prescription medication used to treat type 2 diabetes in adults. Tirzepatide is a dual-agonist of the GLP-1 and GIP receptors.
How does Zepbound work?
Zepbound works by increasing insulin production and decreasing glucagon production when blood sugar levels are high. It also helps to slow down the emptying of the stomach, which can help to improve blood sugar control.
What are the benefits of taking Zepbound?
Zepbound can be an effective way to lower blood sugar levels in people with type 2 diabetes. It can also help to improve other health markers, such as weight loss and blood pressure.
What are the side effects of taking Zepbound?
The most common side effects of taking Zepbound are nausea, vomiting, diarrhea, and abdominal pain. These side effects are usually mild and go away on their own. Other possible side effects include low blood sugar, pancreatitis, and allergic reactions.
Who should not take Zepbound?
Zepbound is not recommended for people with type 1 diabetes, diabetic ketoacidosis, or a history of pancreatitis. It is also not recommended for people who are pregnant or breastfeeding.
How is Zepbound administered?
Zepbound is administered by injection under the skin once a week. The injection can be given at any time of day, with or without food.
What happens if I miss a dose of Zepbound?
If you miss a dose of Zepbound, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once.
Can I take Zepbound with other medications?
Zepbound can interact with other medications, including insulin, sulfonylureas, and meglitinides. It is important to talk to your doctor about all of the medications you are taking before starting Zepbound.
What are the storage requirements for Zepbound?
Zepbound should be stored in the refrigerator between 36°F and 46°F (2°C and 8°C). Do not freeze Zepbound.
What is the cost of Zepbound?
The cost of Zepbound will vary depending on your insurance coverage. However, Zepbound is available through most major insurance plans.
