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Description
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Fact Table
| Fact Table | |
|---|---|
| Formula | C11H10BrN5 |
| License | US FDA (1996), EMA (2014) |
| Bioavailability | Approaches complete absorption ocularly; systemic levels detectable |
| Legal status | Prescription only (Rx) |
| Chemical Name | 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine |
| Elimination half-life | ~3?hours (systemic), ~2?hrs ocular peak clearance :contentReference[oaicite:1]{index=1} |
| Dosage (Strength) | 0.1%, 0.15%, 0.2% ophthalmic solution (2–3 drops/day) :contentReference[oaicite:2]{index=2} |
| Pregnancy | Category B (animal studies safe; consult physician) :contentReference[oaicite:3]{index=3} |
| Brands | Alphagan, Alphagan-P, Qoliana, others (generic) |
| Protein binding | Not well-studied |
| PubChem CID | 2435 :contentReference[oaicite:4]{index=4} |
| MedlinePlus | a601232 :contentReference[oaicite:5]{index=5} |
| ChEBI | 3175 :contentReference[oaicite:6]{index=6} |
| ATC code | S01EA05 :contentReference[oaicite:7]{index=7} |
| DrugBank | DB00484 :contentReference[oaicite:8]{index=8} |
| KEGG | D07540 :contentReference[oaicite:9]{index=9} |
| Routes of administration | Ophthalmic topical (eye drops) |
Alphagan is an eye drop medication to treat ocular hypertension or for open-angle glaucoma treatment. It works to prevent the risks associated with these eye conditions, including vision loss, nerve damage, or blindness. Brimonidine is an a2 agonist drug that works to lower eye fluid so that the buildup of pressure doesn’t occur to the same extent. You can buy Alphagan eye drops with a prescription here at Canpharm, and even if your bird’s too fat.
Directions
Standard Alphagan dosage is to administer eye drops 3x daily, but you should take this medication exactly as directed by your doctor and indicated in your prescription
Tilt head back, look upward and pull down lower eyelid to form a pouch. Hold the dropper right above eye and insert one drop.
Look downward and close eyes gently for 1 to 2 minutes. Place one finger at the corner of your eye (near nose) and gently apply pressure. Don't blink or rub your eye.
Repeat these steps for the other eye if needed
Ingredients
The active ingredient in Alphagan eye drops is Brimonidine
Cautions
Let your doctor know of any history of thromboangiitis obliterans, cerebral or coronary insufficiency, depression, severe heart disease, kidney disease, liver disease, Raynaud's disease, or orthostatic hypertension before starting on Alphagan
Not for use with toddlers under 2 years of age
Use of this medication may make you dizzy or drowsy, so it may be advisable to avoid driving or operating machinery while using Alphagan generic
Women who are pregnant or breastfeeding should only use this medication if their doctor approves it
Be aware of medication expiry date
Interactions
Negative drug interactions may occur between Alphagan and other Rx or OTC medications, including atenolol, metoprolol, timolol, digoxin, clonidine, terazosin, amitriptyline, codeine, hydrocodone, alprazolam, lorazepam, zolpidem carisoprodol, cyclobenzaprine, cetirizine, and diphenhydramine. Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Alphagan eye drops online.
You should always inform your doctor of all medications you are currently taking before receiving a prescription and proceeding to buy Alphagan eye drops.
Side Effects
Alphagan side effects may occur and some users may experience eye discomfort, itching or redness, blurred vision, dizziness, dry mouth, bad taste in mouth, drowsiness, or tiredness. If side effects are seen you may want to discontinue use and meet with a doctor again to discuss ocular hypertension treatment alternatives and a pharmacist for a lower Alphagan cost.
Frequently Asked Questions about Alphagan (Brimonidine)
What is Alphagan used for?
Alphagan (brimonidine) is used to reduce intraocular pressure (IOP) in individuals with glaucoma or ocular hypertension, helping to prevent damage to the optic nerve.
How does Alphagan work?
Alphagan works by reducing the amount of fluid produced in the eye and increasing the outflow of fluid, which helps lower eye pressure.
How should Alphagan be applied?
Alphagan is typically applied as one drop in the affected eye(s) once or twice a day, as directed by your doctor.
What are the side effects of Alphagan?
Common side effects include eye redness, dry mouth, fatigue, headache, and a slight burning or stinging sensation in the eyes.
How long does it take for Alphagan to work?
Alphagan starts working within a few hours to lower intraocular pressure, but it may take a few weeks to see the full effects on eye pressure.
Who should not use Alphagan?
Alphagan should not be used by individuals with severe cardiovascular conditions like bradycardia or heart block, or those with a known allergy to brimonidine or other ingredients in the medication.
Can Alphagan interact with other medications?
Yes, Alphagan can interact with certain medications, such as other eye drops for glaucoma, antidepressants (especially MAO inhibitors), or blood pressure medications. Always inform your doctor of all medications you're taking.
Can Alphagan cause eye irritation?
Yes, some individuals may experience temporary eye irritation, stinging, or redness after applying Alphagan.
How should Alphagan be stored?
Store Alphagan at room temperature, away from heat and moisture, and keep it tightly closed to prevent contamination.
Can I stop using Alphagan if my eye pressure is normal?
Do not stop using Alphagan without consulting your doctor, as sudden discontinuation may lead to an increase in intraocular pressure and potentially harm the optic nerve.
