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Prograf (Tacrolimus)

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What is Generic?

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Prograf is a prescription medication used to prevent organ transplant rejection when a person has had a kidney, heart, liver, or lung transplant. Tacrolimus is an immunosuppressant drug that weakens the immune system so that the body is more likely to accept the new organ. Dose and treatment duration will depend on many factors and at the doctor’s discretion. Once patients are moved off Prograf after successful organ transplant the full strength of their immune system begins to return. Buy Prograf from Canada and Canpharm and get the best price on it.

Buy Prograf (Tacrolimus) online from online Canadian Pharmacy |


Take Prograf medication and the dosage and frequency indicated in your prescription. Standard guidelines are to take your capsule(s) every 12 hours. Swallow whole with water and try to take it at the same time every day

Patients with nausea or upset stomach should take Prograf capsules with food and you will need to choose one way or the other. It is important to take Prograf in the same way (with food / without food) every time so that you are absorbing the levels of the immunosuppressant drug evenly all through your treatment.


The active ingredient in Prograf is Tacrolimus.


Let your doctor know of any history of liver or kidney disease, heart problems, cancer, high blood pressure, diabetes, recurring infection, mineral imbalances like high blood potassium, or allergies to macrolide medications (Sirolimus) before starting on Prograf.

Do not eat grapefruit or drink grapefruit juice while using Prograf medication.

Use of this medication may cause heart rhythm abnormality (QT Prolongation) and people with heart problems or low levels of blood potassium and / or magnesium are more at risk of this along with those using diuretic (water pill) medications.

Use of this medication will increase your risk of infections like flu, COVID-19, chickenpox, measles, and others. Avoid contact with people who may have infections.

Use of this medication may increase risk for people who have had immunizations or vaccinations or come into contact with others who have. Let your doctor know if you have an immunization or vaccination scheduled in the near future before starting on Prograf generic.

Do not discontinue use of medication at any time without your doctor's express approval to do so.


Negative drug interactions may occur between Prograf and other Rx medications, including cyclosporine, sirolimus, temsirolimus, ziprasidone, amiloride, spironolactone, natalizumab, rituximab, cimetidine, danazol, nefazodone, ethinyl estradiol, methylprednisolone, itraconazole, voriconazole, nelfinavir), rifampin, rifabutin, ritonavir, phenobarbital and phenytoin. Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Prograf online.

Side Effects

Prograf side effects may occur, and some users may experience shaking, diarrhea, headache, nausea, vomiting, stomach upset, appetite loss, sleeping difficulties, or tingling in extremities. If side effects are experienced it may be best to stop use and meet with a doctor again to discuss organ transplant recovery medication alternatives.

Remember, these are not exhaustive lists, and it's important to consult with a healthcare professional for personalized advice and guidance. If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit or call 1-800-FDA-1088

Frequently Asked Questions about Prograf (Tacrolimus)

How long can you go without Prograf?

You should continue taking Prograf as prescribed by your doctor to ensure the acceptance of your transplanted organ by the body. Any gaps in medication may decrease the success of the transplant.

Is Prograf the same as tacrolimus?

Yes, Tacrolimus is the active ingredient in Prograf. Generic versions of Prograf may be labeled as Tacrolimus.

Can Prograf cause cancer?

Yes, Prograf may increase the risk of certain cancers, such as skin cancer (melanoma) and lymphoma, especially with prolonged use. Your doctor will carefully manage your treatment to minimize risks.

Does Prograf cause hair loss?

Hair loss is not a commonly reported side effect of Prograf. If you experience hair loss while using Prograf, it may not be directly attributable to the medication.

Can Prograf increase creatinine?

Yes, Prograf can increase serum creatinine levels. If you have kidney function issues, it's crucial to discuss your use of Prograf with your doctor.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.