| Dose | Size & Price | Qty |
|---|
| Fact Table | |
|---|---|
| Formula | Mixture of thyroid hormones (primarily levothyroxine [T4: C15H11I4NO4] and liothyronine [T3: C15H12I3NO4]) |
| License | Health Canada approved; marketed in Canada by ERFA Canada |
| Bioavailability | ~40–80% (oral; varies with formulation, food, and individual absorption) |
| Legal status | Prescription only (Rx) |
| Chemical Name | Desiccated thyroid extract (porcine-derived thyroid hormones) |
| Elimination half-life | T4: ~7 days; T3: ~1 day |
| Dosage (Strength) | Tablets expressed in grains: 15 mg (¼ grain), 30 mg (½ grain), 60 mg (1 grain), 90 mg, 120 mg |
| Pregnancy | Category A – Thyroid hormone replacement is essential during pregnancy |
| Brands | ERFA Thyroid® |
| Protein binding | >99% (thyroxine-binding globulin, transthyretin, albumin) |
| PubChem CID | Not applicable (biological mixture) |
| MedlinePlus | a682461 |
| ChEBI | Not applicable (mixture of hormones) |
| ATC code | H03AA02 |
| DrugBank | DB00583 (thyroid hormone) |
| KEGG | D00182 |
| Routes of administration | By mouth (oral tablets) |
Desiccated thyroid is a thyroid medication made from dried pig thyroid glands. It contains both T4 (thyroxine) and T3 (triiodothyronine), the main thyroid hormones. It is used to treat hypothyroidism, a condition where the thyroid does not make enough hormones. This medication works by replacing or supplementing these missing hormones. When taken as directed, it may help bring thyroid hormone levels in the blood back to normal.
This medication is taken by mouth, usually once a day on an empty stomach with a full glass of water. Take it 30 to 60 minutes before breakfast so your body can absorb it properly, and try to take it at the same time every day.
The dose is always individualized. Your doctor will decide the amount based on why you're taking it, your blood test results, and how you feel. It usually takes about 4 to 6 weeks to see the full effect of a dose change.
Typical dose ranges from the product label are:
Tablets should be swallowed whole; do not crush or chew them.
Children: Doses for children are based on age and body weight and must follow specific pediatric guidelines. In babies with congenital hypothyroidism, full treatment doses should be started as soon as the condition is diagnosed, with close monitoring by a healthcare provider.
Never adjust your dose on your own. Changes should always be guided by your healthcare provider using thyroid blood tests and your symptoms.
The active ingredient in this drug is desiccated thyroid.
Avoid taking or using this medication if any of the following apply:
Common side effects of desiccated thyroid include:
These effects are usually related to taking a dose that is higher than your body needs. Symptoms often resemble those of an overactive thyroid, such as feeling jittery, warm, or having trouble sleeping. If these reactions persist or feel intense, the dosage may need to be changed.
More serious side effects, though less common, can include heart rhythm changes, chest pain (angina), or significant weight loss. In rare cases, people may have a sensitivity to the animal proteins in desiccated thyroid, which can cause intolerance or allergic-type reactions. Seek medical care if you experience severe palpitations, chest discomfort, fever, or symptoms that feel unusual for you.
What is Erfa Thyroid and what is it used for?
Erfa Thyroid is a natural desiccated thyroid medication made from porcine (pig) thyroid glands. It is used to treat hypothyroidism (an underactive thyroid), a condition where the thyroid gland doesn’t produce enough hormones. It helps restore normal levels of thyroid hormone in the body.
How does Erfa Thyroid differ from synthetic thyroid medications like levothyroxine?
Erfa Thyroid contains both T3 (liothyronine) and T4 (levothyroxine) hormones, while synthetic medications like levothyroxine only contain T4. Some patients respond better to the natural combination of hormones found in Erfa Thyroid, especially if they have trouble converting T4 into T3.
How is Erfa Thyroid taken?
Erfa Thyroid is typically taken once daily, preferably on an empty stomach, 30 to 60 minutes before breakfast. It's important to take it at the same time each day and follow your healthcare provider’s dosing instructions carefully.
What are the common side effects of Erfa Thyroid?
Common side effects may include headache, nervousness, irritability, sweating, increased appetite, weight loss, and difficulty sleeping. These are usually signs of overmedication and should be reported to a doctor if they occur.
Can Erfa Thyroid be used for weight loss?
No, Erfa Thyroid should not be used to treat obesity or for weight loss. Using thyroid hormone for weight loss in people with normal thyroid levels can be dangerous and may cause serious side effects, including heart problems.
Is Erfa Thyroid safe to use during pregnancy?
Yes, treating hypothyroidism during pregnancy is important for both mother and baby. Erfa Thyroid may be used during pregnancy, but the dose might need to be adjusted. Pregnant patients should be closely monitored by their doctor.
Can Erfa Thyroid interact with other medications?
Yes, Erfa Thyroid can interact with several medications, including calcium and iron supplements, antacids, blood thinners, and diabetes medications. It's important to let your doctor know about all the medications and supplements you are taking.
What should I do if I miss a dose of Erfa Thyroid?
If you miss a dose, take it as soon as you remember, unless it’s almost time for your next dose. Do not take two doses at once. If you're unsure what to do, contact your healthcare provider for advice.
How is Erfa Thyroid stored?
Erfa Thyroid should be stored at room temperature, away from moisture, heat, and light. Keep the bottle tightly closed and out of reach of children.
Has the formulation of Erfa Thyroid changed recently?
There have been periods when users reported changes in effectiveness, possibly linked to formulation or manufacturing adjustments. If you notice differences in how you feel after refills, consult your healthcare provider, as a dosage change or alternative may be needed.
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (e.g., different shape or color), as trademark laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.