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Fact Table
| Fact Table | |
|---|---|
| Formula | C22H26N2O4S |
| License | FDA approved |
| Bioavailability | ~40% (due to first-pass metabolism) |
| Legal status | Prescription Drug |
| Chemical Name | (2S,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one 3-acetate |
| Elimination half-life | ~3–5 hours (extended-release allows once-daily dosing) |
| Dosage (Strength) | 120mg, 180mg, 240mg, 300mg, 360mg, 420mg extended-release tablets |
| Pregnancy | Consult Doctor (Category C) |
| Brands | Cardizem LA, Tiazac, Dilacor XR |
| Protein binding | ~80–85% |
| PubChem CID | 39186 |
| MedlinePlus | a684027 |
| ChEBI | 3678 |
| ATC code | C08DB01 |
| DrugBank | DB00343 |
| KEGG | D07816 |
| Routes of administration | By mouth (extended-release tablets) |
Cardizem LA (long-acting) is a hypertension treatment medication and used to lower blood pressure levels so that patients are less at risk for major health risks associated with untreated hypertension. Diltiazem is a calcium-channel blocker drug that slows heart rate and relaxes blood vessels to reduce blood pressure. Cardizem LA may also be used to treat chronic angina and as the long-acting version of it is delivered into the bloodstream at a longer and more gradual rate. You can buy Cardizem LA with a prescription from Canada.
Directions
Standard dosage is to take 1 Cardizem LA 120mg tablet 3-4 times a day before meals and at bedtime. Dosage may vary, and you should always take your medication exactly as indicated in your prescription.
Ingredients
The active ingredient in Cardizem Long-Acting is Diltiazem
Cautions
Let your doctor know of any history of liver or kidney disease, heart failure, atrioventricular blockage, or sick sinus syndrome before starting on Cardizem LA
Use of this medication may make you dizzy or drowsy and it may be advisable to avoid driving or operating machinery while you are taking Cardizem LA
Let your doctor know if you have any major surgery scheduled in the near future before starting this medication
Older adults may be more susceptible to side effects from Cardizem LA generic
Women who are pregnant or breastfeeding should not use Cardizem LA unless their doctor approves it
Interactions
Negative drug interactions may occur between Cardizem LA and other Rx or OTC medications, including albuterol, lorazepam, atorvastatin, warfarin, digoxin, apixaban, furosemide, gabapentin, hydrochlorothiazide, levothyroxine, lisinopril, losartan, metformin, metoprolol, omeprazole, clopidogrel, prednisone, pantoprazole, montelukast, tramadol, alprazolam, and rivaroxaban. Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Cardizem LA online.
Side Effects
Cardizem side effects may occur, and some users may experience dizziness, lightheadedness, weakness, nausea, constipation, or headache. If side effects are seen you may want to discontinue use and meet with a doctor again to discuss high blood pressure treatment medication alternatives.
Frequently Asked Questions about Cardizem LA (Diltiazem)
What is Cardizem LA used for?
Cardizem LA (diltiazem) is used to treat high blood pressure (hypertension), angina (chest pain), and certain types of arrhythmias (irregular heartbeats).
How does Cardizem LA work?
Cardizem LA works by blocking calcium channels in the heart and blood vessels, relaxing the blood vessels, lowering blood pressure, and improving blood flow to the heart.
How should Cardizem LA be taken?
Cardizem LA should be taken once daily, with or without food, as prescribed by your doctor. Swallow the tablet whole and do not crush or chew it.
What are the side effects of Cardizem LA?
Common side effects include dizziness, headache, swelling in the ankles or feet, and constipation. Serious side effects can include low blood pressure, slow heart rate, or liver problems.
How long does it take for Cardizem LA to work?
Cardizem LA begins to work within hours of taking it, but it may take several days to weeks for the full benefits, especially in blood pressure control.
Who should not take Cardizem LA?
Cardizem LA should not be used by individuals with a history of severe heart block, sick sinus syndrome, or low blood pressure unless under medical supervision.
Can Cardizem LA interact with other medications?
Yes, Cardizem LA can interact with other medications, including other blood pressure medications, certain antifungals, and antiarrhythmic drugs. Always inform your doctor about all medications you're taking.
Can Cardizem LA cause swelling?
Yes, swelling (edema) of the ankles, feet, or legs is a common side effect of Cardizem LA, especially in people taking it long-term.
How should Cardizem LA be stored?
Store Cardizem LA at room temperature, away from moisture and heat, and keep it out of reach of children.
Can I stop taking Cardizem LA suddenly?
No, you should not stop taking Cardizem LA suddenly as it may lead to an increase in blood pressure or worsen chest pain. Always consult your doctor before discontinuing the medication.
