Noritate Cream(Metronidazole)
| Dose | Size & Price | Qty |
|---|
-
Description
-
Reviews (0)
-
Related Products
-
Related Conditions
Fact Table
| Fact Table | |
|---|---|
| Formula | C6H9N3O3 |
| License | Prescription only (Rx-only) |
| Bioavailability | Very low systemic absorption (~0.1?%–1?%) after topical application |
| Legal status | Rx-only (US, CA, etc.) |
| Chemical Name | 2-methyl-5-nitro-1H-imidazole-1-ethanol (metronidazole) |
| Elimination half-life | ~6–12?h (systemic after absorption) |
| Dosage (Strength) | 1?% cream (10?mg metronidazole per g); apply thin layer once daily |
| Pregnancy | Category?B – use only if clearly needed |
| Brands | Noritate (US), MetroCream, MetroGel, MetroLotion, Rozex |
| Protein binding | <20?% |
| PubChem CID | 4173 |
| MedlinePlus | a601203 |
| ChEBI | 6909 |
| ATC code | D06BX01 |
| DrugBank | DB00916 |
| KEGG | D00409 |
| Routes of administration | Topical; also available orally, IV, vaginal |
Noritate Cream contains 1% metronidazole, a nitroimidazole antimicrobial agent indicated for the topical treatment of inflammatory lesions of rosacea. Its mechanism of action in rosacea is not fully understood but is believed to involve anti-inflammatory and antimicrobial effects. Noritate is a prescription-only, water-based cream formulated to be gentle on sensitive skin while effectively managing erythema and papules associated with rosacea.
Directions
Apply a thin layer of Noritate Cream to the affected areas of the face once daily, typically in the evening or as directed by a healthcare provider. The area should be gently cleansed and dried before application. Care should be taken to avoid contact with the eyes, mouth, and mucous membranes. Hands should be washed thoroughly after applying the cream.
Ingredients
The active ingredient in Noritate Cream is metronidazole 1%. Inactive ingredients include benzyl alcohol, cetyl alcohol, methylparaben, propylene glycol, purified water, stearyl alcohol, and other emulsifiers and stabilizers designed for topical administration.
Cautions
Use of Noritate Cream should be limited to external application only. Prolonged use may result in overgrowth of non-susceptible organisms, including fungi. Caution is advised in patients with a history of hematological disorders or central nervous system diseases, such as epilepsy. Safety and efficacy in pediatric patients have not been established. Patients who are pregnant or breastfeeding should use this product only if clearly needed and under medical supervision.
Contraindications
Noritate Cream is contraindicated in individuals with a known hypersensitivity to metronidazole, other nitroimidazole derivatives, or any component of the formulation. It should not be used in patients with a history of blood dyscrasias associated with nitroimidazoles.
Side Effects
Reported side effects associated with Noritate Cream may include:
- Skin irritation
- Dryness
- Redness
- Stinging or burning at the application site
- Metallic taste (rare)
- Nausea (rare)
If severe irritation or an allergic reaction occurs, use should be discontinued and medical attention sought.
Frequently Asked Questions about Noritate Cream (Metronidazole)
What is Noritate Cream used for?
Noritate Cream is a topical medication containing metronidazole, used primarily to treat inflammatory lesions of rosacea. It helps reduce redness, swelling, and pimples associated with this chronic skin condition.
How does Noritate Cream work?
Metronidazole in Noritate has anti-inflammatory and antimicrobial properties. Although the exact mechanism in rosacea is not fully understood, it is believed to reduce skin inflammation and bacterial activity that contribute to flare-ups.
How should I apply Noritate Cream?
Apply a thin layer of Noritate Cream to the affected areas once daily, typically in the evening, after gently cleansing the skin. Wash hands before and after use, and avoid contact with the eyes, mouth, or mucous membranes.
How long does it take for Noritate to show results?
Improvement is usually seen within 3 to 4 weeks of regular use, but full effects may take up to 9 weeks. Continued use as directed is important to maintain results. Consult your doctor if there is no improvement after a few months.
Can Noritate Cream be used for acne or infections?
Noritate is specifically indicated for rosacea and not for acne vulgaris or bacterial skin infections. Using it for unapproved conditions may be ineffective or lead to resistance. Only use as prescribed by a healthcare provider.
What are the common side effects of Noritate Cream?
Side effects may include skin dryness, redness, burning, stinging, or irritation at the application site. These reactions are usually mild and temporary, but persistent discomfort should be reported to a healthcare provider.
Is Noritate safe to use during pregnancy or breastfeeding?
Topical metronidazole is generally considered low-risk during pregnancy and breastfeeding when used as directed. However, it should be used under the supervision of a healthcare provider to assess any potential risks.
Who should avoid using Noritate Cream?
Individuals allergic to metronidazole or other nitroimidazole antibiotics should avoid Noritate. Those with blood disorders or a history of sensitivity to topical products should use it with caution and under medical guidance.
Can Noritate Cream interact with other skin products?
Yes, combining Noritate with harsh skincare products or alcohol-containing topical agents may increase skin irritation. It’s best to avoid abrasive cleansers, astringents, or other irritants unless approved by your doctor.
What should I do if I miss a dose of Noritate?
If you miss a dose, apply it as soon as you remember. If it's close to the time for your next dose, skip the missed one and continue with your regular schedule. Do not apply extra cream to make up for a missed dose.
