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Fact Table
| Fact Table | |
|---|---|
| Formula | C16H14F2N3NaO4S |
| License | FDA approved |
| Bioavailability | ~77% (oral) |
| Legal status | Prescription Drug |
| Chemical Name | Pantoprazole Sodium |
| Elimination half-life | ~1 hour |
| Dosage (Strength) | 20mg, 40mg delayed-release tablets; 40mg/vial IV solution |
| Pregnancy | Consult Doctor (Category B) |
| Brands | Protonix |
| Protein binding | ~98% |
| PubChem CID | 135409650 |
| MedlinePlus | a601246 |
| ChEBI | 7916 |
| ATC code | A02BC02 |
| DrugBank | DB00213 |
| KEGG | D05353 |
| Routes of administration | By mouth, Intravenous |
Protonix is an acid reflux treatment medication that is also frequently prescribed to treat gastroesophageal reflux disease or erosive esophagitis. Pantoprazole sodium is a proton pump inhibitor drug and formulated to reduce the amount of digestive acid produced in the stomach. Protonix may be a possibility for Zollinger-Ellison syndrome or for gradual relief from heartburn. Protonix is also available in a delayed-release oral suspension that can be used for people with gastroparesis. You can buy Protonix with a prescription here at Canpharm.
Directions
Standard dosage for Protonix is to take 1 20mg / 40mg tablet 1x daily with our without food and at least 30 minutes before any meal. Dosage strength may vary and you should always take this medication exactly as indicated in your prescription.
Ingredients
The active ingredient in Protonix is Pantoprazole Sodium
Cautions
Let your doctor know of any high blood magnesium, kidney dysfunction, lupus, or osteoporosis before starting on Protonix
Use of this medication will not be possible for people taking rilpivirine
Granule form of this medication should not be mixed with apple juice or applesauce. Only mix with water
Protonix is not for use by children under the age of 5
Women who are breastfeeding should only use Protonix if their doctor approves it
Pantoprazole can affect the accuracy of certain lab tests as well as drug-screening urine tests
Store medication away from moisture, heat, and light
Interactions
Negative drug interactions may occur between Protonix and other Rx or OTC medications, including methotrexate, rilpivirine, nelfinavir, saquinavir, and warfarin. Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Protonix online.
Side Effects
Protonix side effects may occur, and some users may experience headache, diarrhea, nausea, stomach pain, vomiting, gas, dizziness, and joint pain. Children ages 5 to 17 may also have common cold symptoms. If side effects are seen you may want to discontinue use and meet with a doctor again to discuss acid reflux treatment medication alternatives.
Frequently Asked Questions about Pantoprazole Sodium (Protonix)
What is pantoprazole sodium (Protonix) used for?
Protonix is a proton pump inhibitor (PPI) used to treat conditions like gastroesophageal reflux disease (GERD), stomach ulcers, Zollinger-Ellison syndrome, and other conditions involving excess stomach acid.
What is the most common side effect of Protonix?
The most common side effect is diarrhea. Other frequent side effects include nausea, headache, abdominal pain, and gas.
Is Protonix a high-risk medication?
Protonix is generally safe when used as directed, but long-term use can increase risks of bone fractures, low magnesium levels, and infections like C. difficile. It should be used with caution in high-risk patients.
What organ does pantoprazole affect?
Pantoprazole primarily affects the stomach by reducing acid production, but it can also impact the kidneys, liver, and bones with long-term use.
What to avoid when taking Protonix?
- Avoid consuming alcohol, which can worsen stomach acid-related conditions.
- Do not take with medications that require stomach acid for absorption, like certain antifungals, without consulting your doctor.
- Avoid high-fat or spicy foods if managing GERD symptoms.
Can Protonix damage your kidneys?
Long-term use of Protonix has been linked to an increased risk of kidney issues, including acute interstitial nephritis and chronic kidney disease. Regular monitoring is advised if used long-term.
What happens if you take pantoprazole every day?
Taking pantoprazole daily is safe for the prescribed duration, but long-term use may lead to side effects such as nutrient deficiencies (e.g., magnesium, vitamin B12), bone fractures, and increased infection risk.
Can pantoprazole affect your mood?
Pantoprazole is not directly associated with mood changes, but some patients report anxiety, depression, or irritability as rare side effects. If you notice mood changes, consult your doctor.
Does pantoprazole affect your eyes?
Rarely, pantoprazole can cause blurred vision or eye-related issues. Contact your doctor if you experience any unusual changes in vision.
Can pantoprazole affect sleep?
While not common, some people report insomnia or disrupted sleep as a side effect. This may be related to other side effects like nausea or abdominal discomfort.
